Anti-PKC alpha + beta 2 (phospho T638) 抗体 (ab59365)


  • 製品名Anti-PKC alpha + beta 2 (phospho T638) antibody
    PKC alpha + beta 2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to PKC alpha + beta 2 (phospho T638)
  • 特異性ab59365 detects endogenous levels of PKC alpha + beta 2 only when phosphorylated at threonine 638.
  • アプリケーション適用あり: ELISA, IHC-Pmore details
  • 種交差性
    交差種: Mouse, Human
    交差が予測される動物種: Rat
  • 免疫原

    Synthesized phosphopeptide derived from human PKC alpha + beta 2 around the phosphorylation site of threonine 638 (VLTPPP).

  • ポジティブ・コントロール
    • Human breast carcinoma tissue
  • 特記事項Store at -20°C for 1 year


  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS (without Mg+2 and Ca+2), 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)Purified from rabbit antiserum by affinity chromatography using epitope specific phosphopeptide. The antibody against non phosphopeptide was removed by chromatography using non phosphopeptide corresponding to the phosphorylation site.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野


Our Abpromise guarantee covers the use of ab59365 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/20000.
IHC-P Use at an assay dependent concentration.


  • 関連性Protein kinase C alpha and protein kinase C beta belong to the protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily. Both contain 1 AGC kinase C terminal domain, 1 C2 domain, 2 phorbol ester/DAG type zinc fingers and 1 protein kinase domain. They are calcium activated, phospholipid dependent, serine and threonine specific enzymes. PKC alpha and may play a role in cell motility. PKC beta may be a novel component of the NF kappa B signaling axis responsible for the survival and activation of B cells after BCR cross linking. Both are activated by diacylglycerol which in turn phosphorylates a range of cellular proteins and both may also serve as the receptor for phorbol esters, a class of tumor promoters. PKC beta has two named isoforms produced by alternative splicing.
  • 細胞内局在Cell Membrane and Cytoplasmic
  • 参照データベース
  • 別名
    • PKC alpha antibody
    • PKC beta antibody
    • PKCA antibody
    • PKCB antibody
    • PRKACA antibody
    • PRKCB antibody
    • PRKCB2 antibody
    • Protein kinase C alpha type antibody
    • Protein kinase C beta antibody
    • Protein kinase C beta type antibody
    • protein kinase C, alpha antibody
    see all

Anti-PKC alpha + beta 2 (phospho T638) antibody 画像

  • ab59365, at a 1/50 dilution, staining human PKC alpha + beta 2 in breast carcinoma, using Immunohistochemistry, Paraffin embedded tissue, in the absence of the immunizing peptide (left image) and in the presence of the immunizing peptide (right image).

Anti-PKC alpha + beta 2 (phospho T638) antibody (ab59365) 使用論文

ab59365 has not yet been referenced specifically in any publications.

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