Anti-PKA beta (catalytic subunit) 抗体 (ab64801)


  • 製品名Anti-PKA beta (catalytic subunit) antibody
    PKA beta (catalytic subunit) 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to PKA beta (catalytic subunit)
  • 特異性Detects endogenous levels of total PKA beta (catalytic subunit) protein.
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    A synthetic peptide derived from an internal region of human PKA beta (catalytic subunit)

  • ポジティブ・コントロール
    • Extracts from Jurkat cells and CoLo205 cells



Our Abpromise guarantee covers the use of ab64801 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
  • 追加情報ELISA: 1/20000.
    WB: 1/500 - 1/1000. Detects a band of approximately 50 kDa (predicted molecular weight: 41 kDa). Other bands are detected when using extracts from CoLo205 cells.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux.
    • 組織特異性Isoform 1 is most abundant in the brain, with low level expression in kidney. Isoform 2 is predominantly expressed in thymus, spleen and kidney. Isoform 3 and isoform 4 are only expressed in the brain.
    • 配列類似性Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.
      Contains 1 AGC-kinase C-terminal domain.
      Contains 1 protein kinase domain.
    • 翻訳後修飾Asn-3 is partially deaminated to Asp giving rise to 2 major isoelectric variants, called CB and CA respectively.
    • 細胞内局在Cytoplasm. Nucleus. Translocates into the nucleus (monomeric catalytic subunit) (By similarity). The inactive holoenzyme is found in the cytoplasm.
    • Information by UniProt
    • 参照データベース
    • 別名
      • cAMP-dependent protein kinase catalytic beta subunit isoform 4ab antibody
      • cAMP-dependent protein kinase catalytic subunit beta antibody
      • KAPCB_HUMAN antibody
      • PKA C beta antibody
      • PKA C-beta antibody
      • PKACB antibody
      • Prkacb antibody
      • protein kinase A catalytic subunit beta antibody
      • Protein kinase cAMP dependent catalytic beta antibody
      see all

    Anti-PKA beta (catalytic subunit) antibody 画像

    • All lanes : Anti-PKA beta (catalytic subunit) antibody (ab64801) at 1/500 dilution

      Lane 1 : Extracts from Jurkat cells at 5-30ug with no immunizing peptide
      Lane 2 : Extracts from CoLo205 cells at 5-30ug with no immunizing peptide
      Lane 3 : CoLo205 cells at 5-30ug with immunizing peptide at 5-10ug

      Predicted band size : 41 kDa
      Observed band size : 50 kDa (why is the actual band size different from the predicted?)

    Anti-PKA beta (catalytic subunit) antibody (ab64801) 使用論文

    ab64801 has not yet been referenced specifically in any publications.

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