製品の概要

  • 製品名
    Anti-PICP antibody [8]
    PICP 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [8] to PICP
  • 特異性
    ab17202 is specific for native PICP from amniotic fluid.
  • アプリケーション
    適用あり: IP, ELISA, Sandwich ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    PICP purified from second trimester amniotic fluid by affinity chromatography.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファー
    Preservative: 15mM Sodium Azide
    Constituents: 0.5M Sodium chloride, 0.01M PBS, pH 7.4
  • Concentration information loading...
  • 精製度
    Protein G purified
  • ポリ/モノ
    モノクローナル
  • クローン名
    8
  • アイソタイプ
    IgG1
  • 軽鎖の種類
    kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab17202 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IP Use at an assay dependent concentration.
ELISA 1/6000.
Sandwich ELISA Use at an assay dependent concentration. Can be paired for Sandwich ELISA with Mouse monoclonal [002-18] to PICP (ab76102). Use as Capture antibody with recommended pair.

ターゲット情報

  • 機能
    Type I collagen is a member of group I collagen (fibrillar forming collagen).
  • 組織特異性
    Forms the fibrils of tendon, ligaments and bones. In bones the fibrils are mineralized with calcium hydroxyapatite.
  • 関連疾患
    Caffey disease
    Ehlers-Danlos syndrome 1
    Ehlers-Danlos syndrome 7A
    Osteogenesis imperfecta 1
    Osteogenesis imperfecta 2
    Osteogenesis imperfecta 3
    Osteogenesis imperfecta 4
    Osteoporosis
    A chromosomal aberration involving COL1A1 is found in dermatofibrosarcoma protuberans. Translocation t(17;22)(q22;q13) with PDGF.
  • 配列類似性
    Belongs to the fibrillar collagen family.
    Contains 1 fibrillar collagen NC1 domain.
    Contains 1 VWFC domain.
  • ドメイン
    The C-terminal propeptide, also known as COLFI domain, have crucial roles in tissue growth and repair by controlling both the intracellular assembly of procollagen molecules and the extracellular assembly of collagen fibrils. It binds a calcium ion which is essential for its function.
  • 翻訳後修飾
    Proline residues at the third position of the tripeptide repeating unit (G-X-P) are hydroxylated in some or all of the chains. Proline residues at the second position of the tripeptide repeating unit (G-P-X) are hydroxylated in some of the chains.
    O-linked glycan consists of a Glc-Gal disaccharide bound to the oxygen atom of a post-translationally added hydroxyl group.
  • 細胞内局在
    Secreted > extracellular space > extracellular matrix.
  • Information by UniProt
  • 参照データベース
  • 別名
    • COL1A1 antibody
    • Alpha 1 type I collagen antibody
    • Alpha-1 type I collagen antibody
    • CO1A1_HUMAN antibody
    • COL1A1 antibody
    • Collagen alpha-1(I) chain antibody
    • Collagen type I alpha 1 antibody
    • Procollagen type I C terminal propeptide antibody
    see all

プロトコール

参考文献

ab17202 has not yet been referenced specifically in any publications.

レビューと Q&A

Thank you for contacting us. Below is the information about our testing discount program. If you will be working in IP, you may also be interested in our new range of VeriBlot secondary antibodies that are specific for native IgGs. With these secondari...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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