保存方法 Shipped at 4°C. Add glycerol to a final volume of 50% for extra stability and aliquot. Store at -20°C. Avoid freeze / thaw cycle.
バッファー Preservative: 0.05% Sodium Azide
Constituents: 5mg/ml BSA, 0.15M Sodium Chloride, 50mM Glycine, 0.2mM Tris, 0.1mM EDTA. pH 7.4
Concentration information loading...
精製度 Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Predicted molecular weight: 50 kDa.
機能 Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate heteromeric ACCN3/ACCN2 channel.
配列類似性 Contains 1 AH domain. Contains 1 PDZ (DHR) domain.
翻訳後修飾 Phosphorylation at Thr-82 appears to inhibit the interaction with AMPA receptors.
細胞内局在 Cytoplasm > perinuclear region. Cell junction > synapse. Also present at excitatory synapses.
Information by UniProt
Anti-PICK1 antibody (ab15001) 使用論文
has not yet been referenced specifically in any publications.
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