製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to PICK1
  • 特異性
    Recognizes PICK1.
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Rat
  • 免疫原

    6xhis tagged fusion protein:

    EKMELLDQKH VQDIVFQLQR FVSTMSKYYN DCYAVLQDAD VFPIEVDLAH TTLAYGPNQG SFTDGEEEDE EEEDGAAREV SKDACGATGP TDKGGSWCDS

    , corresponding to C terminal amino acids 317-416 of Mouse PICK1.

  • ポジティブ・コントロール
    • RIPA lysates from rat brain microsomal preparation.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab15001 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Predicted molecular weight: 50 kDa.

ターゲット情報

  • 機能
    Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate heteromeric ACCN3/ACCN2 channel.
  • 組織特異性
    Ubiquitous.
  • 配列類似性
    Contains 1 AH domain.
    Contains 1 PDZ (DHR) domain.
  • 翻訳後修飾
    Phosphorylation at Thr-82 appears to inhibit the interaction with AMPA receptors.
  • 細胞内局在
    Cytoplasm > perinuclear region. Cell junction > synapse. Also present at excitatory synapses.
  • Information by UniProt
  • 参照データベース
  • 別名
    • dJ1039K5 antibody
    • MGC15204 antibody
    • OTTHUMP00000028509 antibody
    • PICK 1 antibody
    • Pick1 antibody
    • PICK1_HUMAN antibody
    • PRKCA binding protein antibody
    • PRKCA-binding protein antibody
    • PRKCABP antibody
    • Protein interacting with C kinase 1 antibody
    • Protein interacting with PRKCA antibody
    • Protein interacting with PRKCA 1 antibody
    • Protein kinase C alpha binding protein antibody
    • Protein kinase C-alpha-binding protein antibody
    • Protein that interacts with C kinase 1 antibody
    see all

プロトコール

参考文献

ab15001 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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