製品の概要

  • 製品名Anti-PI4 kinase beta antibody [EPR3758(2)]
    PI4 kinase beta 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [EPR3758(2)] to PI4 kinase beta
  • アプリケーション適用あり: WBmore details
    適用なし: Flow Cyt,ICC,IHC-P or IP
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to residues in Human PI4 kinase beta.

  • ポジティブ・コントロール
    • HeLa, SH-SY5Y, BxPC-3 and Jurkat cell lysates
  • 特記事項

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab109418 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000 - 1/10000. Detects a band of approximately 100 kDa (predicted molecular weight: 91 kDa).
  • 追加情報Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
  • ターゲット情報

    • 機能Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation. Involved in Golgi-to-plasma membrane trafficking.
    • 組織特異性Widely expressed with highest levels in heart, skeletal muscle, pancreas, testis and ovary. Weakly expressed in liver.
    • 配列類似性Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.
      Contains 1 PI3K/PI4K domain.
      Contains 1 PIK helical domain.
    • 細胞内局在Endomembrane system. Mitochondrion outer membrane. Rough endoplasmic reticulum membrane. Golgi apparatus. Cytoplasm, perinuclear region. Found in the outer membrane of mitochondria and membranes of the rough endoplasmic reticulum. Recruited to the Golgi complex by the small GTPase ARF to stimulate the synthesis of phosphatidylinositol 4,5-bisphosphate (PIP2) on the Golgi complex.
    • Information by UniProt
    • 参照データベース
    • 別名
      • DKFZp686O1820 antibody
      • FLJ30129 antibody
      • NPIK antibody
      • Phosphatidylinositol 4 kinase beta antibody
      • Phosphatidylinositol 4 kinase catalytic beta antibody
      • Phosphatidylinositol 4 kinase catalytic beta polypeptide antibody
      • Phosphatidylinositol 4 kinase wortmannin sensitive antibody
      • Phosphatidylinositol 4-kinase beta antibody
      • PI4K BETA antibody
      • PI4K-beta antibody
      • PI4K92 antibody
      • PI4KB antibody
      • PI4KB_HUMAN antibody
      • PI4Kbeta antibody
      • PI4KIIIbeta antibody
      • PIK4CB antibody
      • PtdIns 4 kinase antibody
      • PtdIns 4-kinase beta antibody
      • Type III phosphatidylinositol 4 kinase beta antibody
      see all

    Anti-PI4 kinase beta antibody [EPR3758(2)] 画像

    • All lanes : Anti-PI4 kinase beta antibody [EPR3758(2)] (ab109418) at 1/1000 dilution

      Lane 1 : HeLa cell lysate
      Lane 2 : SH-SY5Y cell lysate
      Lane 3 : BxPC-3 cell lysate
      Lane 4 : Jurkat cell lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 91 kDa

    Anti-PI4 kinase beta antibody [EPR3758(2)] (ab109418) 使用論文

    This product has been referenced in:
    • Téoulé F  et al. The Golgi protein ACBD3, an interactor for poliovirus protein 3A, modulates poliovirus replication. J Virol 87:11031-46 (2013). Read more (PubMed: 23926333) »

    See 1 Publication for this product

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    There are currently no Abreviews or Questions for ab109418.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"