製品の概要

  • 製品名Anti-PHOX2A antibody
    PHOX2A 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to PHOX2A
  • アプリケーション適用あり: WB, ICC/IFmore details
  • 種交差性
    交差種: Rat, Human
  • 免疫原

    Recombinant fragment: MDYSYLNSYD SCVAAMEASA YGDFGACSQP GGFQYSPLRP AFPAAGPPCP ALGSSNCALG ALRDHQPAPY SAVPYKFFPE PSGLHEKRKQ , corresponding to amino acids 1-91 of Human PHOX2A

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab54847 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 30 kDa.
ICC/IF Use a concentration of 10 µg/ml.

ターゲット情報

  • 機能May be involved in regulating the specificity of expression of the catecholamine biosynthetic genes. Acts as a transcription activator/factor. Could maintain the noradrenergic phenotype.
  • 関連疾患Defects in PHOX2A are the cause of congenital fibrosis of extraocular muscles type 2 (CFEOM2) [MIM:602078]. CFEOM encompasses several different inherited strabismus syndromes characterized by congenital restrictive ophthalmoplegia affecting extraocular muscles innervated by the oculomotor and/or trochlear nerves. CFEOM is characterized clinically by anchoring of the eyes in downward gaze, ptosis, and backward tilt of the head. CFEOM2 may result from the aberrant development of the oculomotor (nIII), trochlear (nIV) and abducens (nVI) cranial nerve nuclei.
  • 配列類似性Belongs to the paired homeobox family.
    Contains 1 homeobox DNA-binding domain.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Aristaless homeobox (Drosophila) fibrosis of extraocular muscles congenital 2 autosomal recessive antibody
    • Aristaless homeobox gene homolog (Drosophila) antibody
    • Aristaless homeobox homolog antibody
    • Aristaless homeobox protein homolog antibody
    • ARIX 1 homeodomain protein antibody
    • ARIX antibody
    • Arix homeodomain protein antibody
    • ARIX1 homeodomain protein antibody
    • CFEOM 2 antibody
    • CFEOM2 antibody
    • FEOM 2 antibody
    • FEOM2 antibody
    • Fibrosis of extraocular muscles congenital 2 autosomal recessive antibody
    • MGC52227 antibody
    • NCAM 2 antibody
    • NCAM2 antibody
    • Paired like (aristaless) Homeobox 2A antibody
    • Paired like homeobox 2a antibody
    • Paired mesoderm homeobox 2a antibody
    • Paired mesoderm homeobox protein 2A antibody
    • Paired-like homeobox 2A antibody
    • PHOX 2A antibody
    • Phox2 antibody
    • Phox2a antibody
    • PHX2A_HUMAN antibody
    • Pmx 2a antibody
    • Pmx2 antibody
    • Pmx2a antibody
    see all

Anti-PHOX2A antibody 画像



  • Predicted band size : 30 kDa
    PHOX2A antibody (ab54847) at 1ug/lane + PC-12 cell lysate at 25ug/lane.
  • ab54847 at 10 ug/ml staining in human Hela cells by Immunocytochemistry / Immunofluorescence.

Anti-PHOX2A antibody (ab54847) 使用論文

This product has been referenced in:
  • Liang H  et al. CtBP2 Downregulation during Neural Crest Specification Induces Expression of Mitf and REST, Resulting in Melanocyte Differentiation and Sympathoadrenal Lineage Suppression. Mol Cell Biol 31:955-70 (2011). WB ; Quail . Read more (PubMed: 21199918) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"