Anti-Phosphoserine phosphatase 抗体 [3G12] (ab48512)

製品の概要

  • 製品名
    Anti-Phosphoserine phosphatase antibody [3G12]
    Phosphoserine phosphatase 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [3G12] to Phosphoserine phosphatase
  • 特異性
    This antibody is specific for D- and L- phosphoserine
  • アプリケーション
    適用あり: ELISA, WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 1-225 of Human Phosphoserine phosphatase, purified from E. coli

  • ポジティブ・コントロール
    • Cell lysates of Mouse brain

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab48512 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA Use at an assay dependent dilution.
WB 1/1000 - 1/2000. Detects a band of approximately 26 kDa (predicted molecular weight: 25 kDa).

ターゲット情報

  • 機能
    Catalyzes the last step in the biosynthesis of serine from carbohydrates. The reaction mechanism proceeds via the formation of a phosphoryl-enzyme intermediates.
  • パスウェイ
    Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 3/3.
  • 関連疾患
    Defects in PSPH are the cause of phosphoserine phosphatase deficiency (PSPHD)[MIM:614023]. A disorder that results in pre- and postnatal growth retardation, moderate psychomotor retardation and facial features suggestive of Williams syndrome.
  • 配列類似性
    Belongs to the SerB family.
  • Information by UniProt
  • 参照データベース
  • 別名
    • EC 3.1.3.3 antibody
    • L 3 phosphoserine phosphatase antibody
    • L-3-phosphoserine phosphatase antibody
    • O phosphoserine phosphohydrolase antibody
    • O-phosphoserine phosphohydrolase antibody
    • Phosphoserine phosphatase antibody
    • Phosphoserine phosphatase deficiency, included antibody
    • PSP antibody
    • PSPase antibody
    • Psph antibody
    • PSPHD antibody
    • SERB_HUMAN antibody
    see all

画像

  • Anti-Phosphoserine phosphatase antibody [3G12] (ab48512) at 1/1000 dilution + Cell lysates of Mouse brain (30µg)

    Secondary
    goat anti-mouse secondary antibody conjugated to HRP
    Developed using the ECL technique

    Predicted band size : 25 kDa
    Observed band size : 26 kDa (why is the actual band size different from the predicted?)

プロトコール

参考文献

ab48512 has not yet been referenced specifically in any publications.

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