製品の概要

  • 製品名Anti-Phosphoserine antibody (Biotin)
    Phosphoserine 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Phosphoserine (Biotin)
  • 標識Biotin
  • 特異性Specifically recognizes both free-phosphoserine, serine-phosphorylated peptide and proteins. Does not cross-react with ATP, phosphotyrosine, peptidyl phosphothreonine and serine. Slight cross-reactivity with free phosphothreonine. Readily reacts to known phosphoproteins such as phosvitin and alpha casein.
  • アプリケーション適用あり: WB, IP, ELISAmore details
  • 種交差性
    交差種: Species independent
  • 免疫原

    BSA and KLH-phosphoserine conjugates.

  • ポジティブ・コントロール
    • Use Mouse brain extract for Western Blotting or synthetic phosphopeptide or phosvitin for ELISA.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab9335 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 4 µg/ml. Do not use milk as a blocking agent or in diluents, as milk casein is phosphorylated at several serine residues. BSA is recommended instead.
IP Use at an assay dependent dilution.
ELISA Use a concentration of 0.5 µg/ml.

ターゲット情報

  • 関連性Changes in the serine/threonine phosphorylation state of a protein in response to various external stimuli can have profound effects on cellular signal transduction, apoptosis and carcinogenesis. The reagents, including phosphorylated protein/peptides, antibodies against the phosphospecific amino acid, are important tools to explore the activation of serine, threonine or tyrosine containing proteins. An aberrant protein phosphorylation is a hallmark of human disease, and the enzymes, particularly protein kinases, which control protein phosphorylation are recognized as a major new drug target family.
  • 別名
    • phospho-Ser antibody
    • pS antibody
    • pSER antibody

Anti-Phosphoserine antibody (Biotin) (ab9335) 使用論文

This product has been referenced in:
  • Phillips JE  et al. Glucocorticoid-induced osteogenesis is negatively regulated by Runx2/Cbfa1 serine phosphorylation. J Cell Sci 119:581-91 (2006). WB . Read more (PubMed: 16443755) »

See 1 Publication for this product

Product Wall

All the information that we have regarding ab9335 is located on our online datasheet. Ab9335 specifically recognizes both free-phosphoserine, serine-phosphorylated peptide and proteins, and for a positive control it is recommended to use mouse brain ex...

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Thank you for your enquiry. The anti-phosphoserine antibodies will not cross-react with phosphotidylserine and other phospholipids.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"