Anti-Phosphoserine 抗体 [B106.1] (ab7851)
Key features and details
- Mouse monoclonal [B106.1] to Phosphoserine
- Suitable for: WB
- Reacts with: Species independent
- Isotype: IgG1
製品の概要
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製品名
Anti-Phosphoserine antibody [B106.1]
Phosphoserine 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [B106.1] to Phosphoserine -
由来種
Mouse -
特異性
This antibody detects free and conjugated phosphoserine as well as phosphoserine in modified cellular proteins. It does not cross react with nonphosphorylated serine or with phosphotyrosine or phosphothreonine, neither does it cross react with AMP or ATP. However, due to steric hinderance, certain proteins known to contain phosphorylated serine may not be recognized by this antibody. -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Species independent -
免疫原
Chemical/ Small Molecule corresponding to Phosphoserine conjugated to Keyhole Limpet Haemocyanin (KLH).
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ポジティブ・コントロール
- For immunoblotting we recommend extract of rat brain cortex.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.40
Preservative: 0.1% Sodium azide
Constituent: PBS -
Concentration information loading...
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精製度
Protein G purified -
ポリ/モノ
モノクローナル -
クローン名
B106.1 -
アイソタイプ
IgG1 -
軽鎖の種類
unknown -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab7851の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB | (1) |
1/50.
Do not use milk as a blocking agent or in diluents, as milk casein is phosphorylated at several serine residues. BSA is recommended instead. |
特記事項 |
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WB
1/50. Do not use milk as a blocking agent or in diluents, as milk casein is phosphorylated at several serine residues. BSA is recommended instead. |
ターゲット情報
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関連性
Changes in the serine/threonine phosphorylation state of a protein in response to various external stimuli can have profound effects on cellular signal transduction, apoptosis and carcinogenesis. The reagents, including phosphorylated protein/peptides, antibodies against the phosphospecific amino acid, are important tools to explore the activation of serine, threonine or tyrosine containing proteins. An aberrant protein phosphorylation is a hallmark of human disease, and the enzymes, particularly protein kinases, which control protein phosphorylation are recognized as a major new drug target family. -
別名
- phospho-Ser antibody
- pS antibody
- pSER antibody
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab7851 は 2 報の論文で使用されています。
- Wu Y et al. Activation of AMPKa2 in adipocytes is essential for nicotine-induced insulin resistance in vivo. Nat Med 21:373-82 (2015). WB, IP . PubMed: 25799226
- Gupta S et al. Kinase-actuated immunoaggregation of Peptide-conjugated gold nanoparticles. Small 6:1509-13 (2010). PubMed: 20578112