製品の概要

  • 製品名Anti-PHF17 antibody
    PHF17 一次抗体 製品一覧
  • 製品の詳細
    Mouse polyclonal to PHF17
  • アプリケーション適用あり: WB, ICC/IFmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length PHF17 protein (Human)

  • ポジティブ・コントロール
    • Hela cells and 293T cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab66968 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Detects a band of approximately 65 kDa (predicted molecular weight: 96 kDa).
ICC/IF Use a concentration of 10 µg/ml. Requires purification with Protein A prior to ICC/IF.

ターゲット情報

  • 機能Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Transcriptional coactivator it may also promote acetylation of nucleosomal histone H4 by KAT5. Promotes apoptosis. May act as a renal tumor suppressor.
  • 組織特異性Highly expressed in kidney. Also present in pancreas, liver and heart (at protein level). Down-regulated in renal cancer cells.
  • 配列類似性Belongs to the JADE family.
    Contains 2 PHD-type zinc fingers.
  • ドメインThe 2 PHD-type zinc fingers are required for transcriptional activity.
  • 細胞内局在Cytoplasm. Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • FLJ22479 antibody
    • Gene for apoptosis and differentiation in epithelia antibody
    • JADE1 antibody
    • JADE1_HUMAN antibody
    • KIAA1807 antibody
    • OTTHUMP00000219842 antibody
    • OTTHUMP00000219934 antibody
    • OTTHUMP00000219935 antibody
    • OTTHUMP00000219936 antibody
    • PHD finger protein 17 antibody
    • PHD protein Jade 1 antibody
    • Phf17 antibody
    • Protein Jade 1 antibody
    • Protein Jade-1 antibody
    see all

Anti-PHF17 antibody 画像

  • Immunofluorescence of ab66968 on HeLa cells. (purified antibody concentration of 10ug/ml)
  • All lanes : Anti-PHF17 antibody (ab66968) at 1/500 dilution

    Lane 1 : PHF17 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 96 kDa
    Observed band size : 65 kDa (why is the actual band size different from the predicted?)

Anti-PHF17 antibody (ab66968) 使用論文

ab66968 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"