製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to PHF17
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Mouse
    交差が予測される動物種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within N terminal amino acids 20-51 of Human PHF17 (NP_079176.2, NP_955352.1).

  • ポジティブ・コントロール
    • Mouse heart tissue lysates

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab116018 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 96 kDa.

ターゲット情報

  • 機能
    Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Transcriptional coactivator it may also promote acetylation of nucleosomal histone H4 by KAT5. Promotes apoptosis. May act as a renal tumor suppressor.
  • 組織特異性
    Highly expressed in kidney. Also present in pancreas, liver and heart (at protein level). Down-regulated in renal cancer cells.
  • 配列類似性
    Belongs to the JADE family.
    Contains 2 PHD-type zinc fingers.
  • ドメイン
    The 2 PHD-type zinc fingers are required for transcriptional activity.
  • 細胞内局在
    Cytoplasm. Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • FLJ22479 antibody
    • Gene for apoptosis and differentiation in epithelia antibody
    • Jade family PHD finger 1 antibody
    • JADE1 antibody
    • JADE1_HUMAN antibody
    • KIAA1807 antibody
    • OTTHUMP00000219842 antibody
    • OTTHUMP00000219934 antibody
    • OTTHUMP00000219935 antibody
    • OTTHUMP00000219936 antibody
    • PHD finger protein 17 antibody
    • PHD protein Jade 1 antibody
    • Phf17 antibody
    • Protein Jade 1 antibody
    • Protein Jade-1 antibody
    see all

画像

  • Anti-PHF17 antibody (ab116018) at 1/100 dilution + Mouse heart tissue lysates at 35 µg

    Predicted band size : 96 kDa

プロトコール

参考文献

ab116018 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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