製品の概要

  • 製品名Anti-Phex antibody
    Phex 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Phex
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Recombinant protein fragment corresponding to a region within amino acids 1 and 325 of Human Phex.

  • ポジティブ・コントロール
    • Molt-4 cells

法規制情報

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab96072 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/3000. Predicted molecular weight: 86 kDa.

ターゲット情報

  • 機能Probably involved in bone and dentin mineralization and renal phosphate reabsorption.
  • 組織特異性Lymphocytes and fetal brain; not in adult brain, placenta, skeletal muscle and pancreas; not in adult and fetal heart, lung, liver and kidney.
  • 関連疾患Defects in PHEX are a cause of X-linked hypophosphatemic rickets (HYP) [MIM:307800]. HYP is an X-linked dominant disorder characterized by impaired phosphate uptake in the kidney, which is likely to be caused by abnormal regulation of sodium phosphate cotransport in the proximal tubules. Clinical manifestations include skeletal deformities, growth failure, craniosynostosis, paravertebral calcifications, pseudofractures in lower extremities, and muscular hypotonia with onset in early childhood. X-linked hypophosphatemic rickets is the most common form of hypophosphatemia with an incidence of 1 in 20000.
  • 配列類似性Belongs to the peptidase M13 family.
  • 細胞内局在Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • HPDR antibody
    • HPDR1 antibody
    • HYP antibody
    • HYP1 antibody
    • LXHR antibody
    • Metalloendopeptidase homolog PEX antibody
    • PEX antibody
    • Phex antibody
    • PHEX_HUMAN antibody
    • Phosphate regulating endopeptidase homolog X linked antibody
    • Phosphate regulating gene with homologies to endopeptidases on the X chromosome antibody
    • Phosphate-regulating neutral endopeptidase antibody
    • Vitamin D-resistant hypophosphatemic rickets protein antibody
    • X-linked hypophosphatemia protein antibody
    • XLH antibody
    see all

Anti-Phex antibody 画像

  • Anti-Phex antibody (ab96072) at 1/1000 dilution + Molt-4 cell lysate at 30 µg

    Predicted band size : 86 kDa

Anti-Phex antibody (ab96072) 使用論文

ab96072 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab96072.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"