製品の概要
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製品名Anti-PGRPS antibody
PGRPS 一次抗体 製品一覧 -
製品の詳細Goat polyclonal to PGRPS
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由来種Goat
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アプリケーション適用あり: WB, IHC-Pmore details
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種交差性交差種: Human
交差が予測される動物種: Dog
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免疫原
Synthetic peptide:
C-PGNQLYHLIQN
, corresponding to C terminal amino acids 179-189 of human PGRPS (NP_005082.1). -
ポジティブ･コントロール
- Jurkat cell lysate.
製品の特性
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製品の状態Liquid
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保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
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バッファーPreservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris saline, pH 7.3 -
Concentration information loading... -
精製度Immunogen affinity purified
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特記事項（精製）ab82163 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
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ポリ/モノポリクローナル
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アイソタイプIgG
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研究分野
関連製品
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Compatible Secondaries
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Positive Controls
アプリケーション
Our Abpromise guarantee covers the use of ab82163 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | Use a concentration of 0.3 - 1 µg/ml. Predicted molecular weight: 22 kDa. | |
| IHC-P | Use a concentration of 3 - 6 µg/ml. |
ターゲット情報
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機能Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity.
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組織特異性Highly expressed in bone marrow. Weak expression found in kidney, liver, small intestine, spleen, thymus, peripheral leukocyte, lung, fetal spleen and neutrophils.
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配列類似性Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
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翻訳後修飾N-glycosylated. N-glycosylation is required for bactericidal activity.
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細胞内局在Secreted. Cytoplasmic granule.
- Information by UniProt
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参照データベース
- Entrez Gene: 8993 Human
- Omim: 604963 Human
- SwissProt: O75594 Human
- Unigene: 137583 Human
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別名
- MGC126894 antibody
- MGC126896 antibody
- Peptidoglycan recognition protein 1 antibody
see all
画像
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Western blot - PGRPS antibody (ab82163)Anti-PGRPS antibody (ab82163) at 0.3 µg/ml + Jurkat cell lysate at 35 µg
Predicted band size: 22 kDa
Observed band size: 30 kDa (why is the actual band size different from the predicted?)
The observed molecular weight corresponds to earlier findings in literature with different antibodies (Lu et al, J Biol Chem. 2006 Mar 3;281(9):5895-907; PMID: 16354652). -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PGRPS antibody (ab82163)ab82163 at 3.8 µg/ml staining PGRPS in Human spleen by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections). Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
参考文献
ab82163 has not yet been referenced specifically in any publications.
レビューと Q&A
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"