製品の概要

  • 製品名Anti-PGRPS antibody
    PGRPS 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to PGRPS
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Dog
  • 免疫原

    Synthetic peptide:

    PGNQLYHLIQN

    by a Cysteine residue linker, corresponding to C terminal amino acids 179-189 of Human PGRPS (NP_005082.1).

  • ポジティブ・コントロール
    • Human spleen tissue; Jurkat cell lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab113625 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 30 kDa (predicted molecular weight: 22 kDa). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Lu et al, J Biol Chem. 2006 Mar 3;281(9):5895-907; PMID: 16354652).
IHC-P Use a concentration of 3.75 µg/ml.

ターゲット情報

  • 機能Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity.
  • 組織特異性Highly expressed in bone marrow. Weak expression found in kidney, liver, small intestine, spleen, thymus, peripheral leukocyte, lung, fetal spleen and neutrophils.
  • 配列類似性Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
  • 翻訳後修飾N-glycosylated. N-glycosylation is required for bactericidal activity.
  • 細胞内局在Secreted. Cytoplasmic granule.
  • Information by UniProt
  • 参照データベース
  • 別名
    • MGC126894 antibody
    • MGC126896 antibody
    • Peptidoglycan recognition protein 1 antibody
    • Peptidoglycan recognition protein antibody
    • Peptidoglycan recognition protein short antibody
    • PGLYRP antibody
    • PGLYRP1 antibody
    • PGRP antibody
    • PGRP S antibody
    • PGRP-S antibody
    • PGRP1_HUMAN antibody
    • PHRP, short antibody
    • SBBI68 antibody
    • TAG7 antibody
    • TNF superfamily, member 3 (LTB)-like (peptidoglycan recognition protein) antibody
    • TNFSF 3L antibody
    • TNFSF3L antibody
    • UNQ639/PRO1269 antibody
    see all

Anti-PGRPS antibody 画像

  • Anti-PGRPS antibody (ab113625) at 0.3 µg/ml + Jurkat cell lysate at 35 µg
    Developed using the ECL technique

    Predicted band size : 22 kDa
    Observed band size : 30 kDa (why is the actual band size different from the predicted?)
  • ab113625 at 3.75ug/ml staining PGRPS in Formalin-fixed, Paraffin-embedded Human spleen tissue by Immunohistochemistry.

Anti-PGRPS antibody (ab113625) 使用論文

ab113625 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"