製品の概要

  • 製品名
    Anti-PGP9.5 antibody - Neuronal Marker
    PGP9.5 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to PGP9.5 - Neuronal Marker
  • 特異性
    Ab11145 recognises human protein gene product 9.5 (PGP9.5).
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Rat, Human
    交差が予測される動物種: Mouse, Horse, Guinea pig, Cow, Pig
  • 免疫原

    Synthetic peptide:

    NFRKKQIEELKGQEVSPK

    , corresponding to amino acids 46 - 63 of Human PGP9.5.

  • ポジティブ・コントロール
    • Cytoplasm of neurons. Soluble brain protein extract.
  • 特記事項
    This product should be stored undiluted. Storage in frost-free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab11145 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use at an assay dependent dilution. Detects a band of approximately 27 kDa (predicted molecular weight: 26.8 kDa).

ターゲット情報

  • 機能
    Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity.
  • 組織特異性
    Found in neuronal cell bodies and processes throughout the neocortex (at protein level). Expressed in neurons and cells of the diffuse neuroendocrine system and their tumors. Weakly expressed in ovary. Down-regulated in brains from Parkinson disease and Alzheimer disease patients.
  • 関連疾患
    Parkinson disease 5
    Neurodegeneration with optic atrophy, childhood-onset
  • 配列類似性
    Belongs to the peptidase C12 family.
  • 翻訳後修飾
    O-glycosylated.
  • 細胞内局在
    Cytoplasm. Endoplasmic reticulum membrane. About 30% of total UCHL1 is associated with membranes in brain.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Epididymis luminal protein 117 antibody
    • Epididymis secretory protein Li 53 antibody
    • HEL 117 antibody
    • HEL S 53 antibody
    • NDGOA antibody
    • Neuron cytoplasmic protein 9.5 antibody
    • OTTHUMP00000218137 antibody
    • OTTHUMP00000218139 antibody
    • OTTHUMP00000218140 antibody
    • OTTHUMP00000218141 antibody
    • Park 5 antibody
    • PARK5 antibody
    • PGP 9.5 antibody
    • PGP9.5 antibody
    • PGP95 antibody
    • Protein gene product 9.5 antibody
    • Ubiquitin C terminal esterase L1 antibody
    • Ubiquitin C terminal hydrolase antibody
    • Ubiquitin C terminal hydrolase L1 antibody
    • Ubiquitin carboxyl terminal esterase L1 antibody
    • Ubiquitin carboxyl terminal hydrolase isozyme L1 antibody
    • Ubiquitin carboxyl-terminal hydrolase isozyme L1 antibody
    • Ubiquitin thioesterase L1 antibody
    • Ubiquitin thiolesterase antibody
    • Ubiquitin thiolesterase L1 antibody
    • UCH-L1 antibody
    • UCHL1 antibody
    • UCHL1_HUMAN antibody
    see all

プロトコール

Anti-PGP9.5 antibody - Neuronal Marker (ab11145) 使用論文

This product has been referenced in:
  • Harriott AM & Gold MS Serotonin type 1D receptors (5HTR) are differentially distributed in nerve fibres innervating craniofacial tissues. Cephalalgia 28:933-44 (2008). WB ; Rat . Read more (PubMed: 18557979) »

See 1 Publication for this product

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There are currently no Abreviews or Questions for ab11145.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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