機能Probably plays a specific functional role in the rods and/or cones of photoreceptors. It may be the enzyme involved in the resynthesis of cGMP required for recovery of the dark state after phototransduction.
組織特異性Retina. Localized exclusively in the outer nuclear layer and inner segments of the rod and cone photoreceptor cells.
配列類似性Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. Contains 1 guanylate cyclase domain. Contains 1 protein kinase domain.
ドメインThe protein kinase domain is predicted to be catalytically inactive.
翻訳後修飾There are 9 conserved cysteine residues in sensory guanylate cyclases, 6 in the extracellular domain, which may be involved in intra- or interchain disulfide bonds.