製品の概要

  • 製品名Anti-PGC1 beta antibody
    PGC1 beta 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to PGC1 beta
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Cow, Rhesus monkey, Marmoset (common)
  • 免疫原

    Synthetic peptide: AGNDCGALLDEELS, corresponding to amino acids 2-15 of Human PGC1 beta (NP_573570.3).

  • ポジティブ・コントロール
    • Human Heart, Human Spleen
  • 特記事項

    This product may be covered by one or more of the following U.S. Patents.

    6,166,192
    6,426,411
    6,525,178
    6,872,391
    6,908,987
    7,250,283
    7,091,006
    7,354,738
    8,105,774
    8,445,233

     

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab118603 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use a concentration of 3.75 - 7.5 µg/ml.

ターゲット情報

  • 機能Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcritional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be involved in fat oxidation and non-oxidative glucose metabolism and in the regulation of energy expenditure. Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner.
  • 組織特異性Ubiquitous with higher expression in heart, brain and skeletal muscle.
  • 配列類似性Contains 1 RRM (RNA recognition motif) domain.
  • ドメインContains 2 Leu-Xaa-Xaa-Leu-Leu (LXXLL) motif, which are usually required for the association with nuclear receptors.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • PERC antibody
    • peroxisome proliferative activated receptor, gamma, coactivator 1, antibody
    • peroxisome proliferator-activated receptor gamma coactivator 1 beta antibody
    • Peroxisome proliferator-activated receptor gamma coactivator 1-beta antibody
    • peroxisome proliferator-activated receptor gamma, coactivator 1 beta antibody
    • PGC-1(beta) antibody
    • PGC-1-beta antibody
    • PGC-1-related estrogen receptor alpha coactivator antibody
    • PGC1 antibody
    • PPAR gamma coactivator-1beta antibody
    • PPAR-gamma coactivator 1-beta antibody
    • PPARGC-1-beta antibody
    • PPARGC1 antibody
    • Ppargc1b antibody
    • PRGC2_HUMAN antibody
    see all

Anti-PGC1 beta antibody 画像

  • ab118603 at 3.75 µg/ml staining PGC1 beta in Human Heart by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue.
  • ab118603 at 3.75 &microg/ml staining PGC1 beta in Human Skeletal Muscle by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue.

Anti-PGC1 beta antibody (ab118603) 使用論文

ab118603 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab118603.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"