製品の概要

  • 製品名Anti-PGAM2 antibody
    PGAM2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to PGAM2
  • 特異性The immunogen sequence shows 81% homology with PGAM1, so cross-reactivity with PGAM1 cannot be excluded. However, cross-reactivity has not been tested.
  • アプリケーション適用あり: WB, ICC/IFmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Cow, Pig
  • 免疫原

    Recombinant fragment, corresponding to a region within amino acids 1-203 of Human PGAM2 (NP_000281)

  • ポジティブ・コントロール
    • H1299 or HeLa lysates A549 cells (IF)

法規制情報

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: 0.01% Thimerosal (merthiolate)
    Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab97800 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/3000. Predicted molecular weight: 29 kDa.
ICC/IF 1/100 - 1/200.

ターゲット情報

  • 機能Interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase) and EC 3.1.3.13 (phosphatase), but with a reduced activity.
  • 組織特異性In mammalian tissues there are two types of phosphoglycerate mutase isozymes: type-M in muscles and type-B in other tissues.
  • 関連疾患Defects in PGAM2 are the cause of glycogen storage disease type 10 (GSD10) [MIM:261670]. A metabolic disorder characterized by myoglobinuria, increased serum creatine kinase levels, decreased phosphoglycerate mutase activity, myalgia, muscle pain, muscle cramps and excercise intolerance.
  • 配列類似性Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
  • Information by UniProt
  • 参照データベース
  • 別名
    • BPG dependent PGAM 2 antibody
    • BPG-dependent PGAM 2 antibody
    • GSD10 antibody
    • MGC88743 antibody
    • Muscle specific phosphoglycerate mutase antibody
    • Muscle-specific phosphoglycerate mutase antibody
    • OTTHUMP00000207787 antibody
    • PGAM 2 antibody
    • PGAM M antibody
    • PGAM-M antibody
    • Pgam2 antibody
    • PGAM2_HUMAN antibody
    • PGAMM antibody
    • phosphoglycerate mutase 2 (muscle) antibody
    • Phosphoglycerate mutase 2 antibody
    • Phosphoglycerate mutase isozyme M antibody
    see all

Anti-PGAM2 antibody 画像

  • All lanes : Anti-PGAM2 antibody (ab97800) at 1/10000 dilution

    Lane 1 : H1299 whole cell lysate
    Lane 2 : HeLa whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 29 kDa
  • Immunofluorescence analysis of paraformaldehyde-fixed A549, using ab97800 at 1/200 dilution. Lower image was also merged with DNA probe.

Anti-PGAM2 antibody (ab97800) 使用論文

This product has been referenced in:

See 1 Publication for this product

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I am sorry for the unclear information on the datashet. As requested, I have issued a free of cha...

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The lab confirmed that they have not done specificity tests for ab97800 for cross-reactivity with PGAM1. They BLASTed the immunogen sequence with PGAM1, which shows 81% homology, so they could not exclude cro...

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