製品の概要

  • 製品名Anti-PEX7 antibody
    PEX7 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to PEX7
  • アプリケーション適用あり: WB, ELISA, IHC-Pmore details
  • 種交差性
    交差種: Mouse, Human
    交差が予測される動物種: Rat
  • 免疫原

    Synthetic peptide derived from the internal region of Human PEX7.

  • ポジティブ・コントロール
    • Extracts from NIH/3T3 cells. Human breast carcinoma tissue.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)ab92779 was affinity-purified from rabbit antiserum by affinity-chromatography using an epitope-specific immunogen
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab92779 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ELISA
IHC-P
  • 追加情報ELISA: 1/40000.
    IHC-P: 1/50 - 1/100.
    WB: 1/500 - 1/1000. Predicted molecular weight: 36 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Binds to the N-terminal PTS2-type peroxisomal targeting signal and plays an essential role in peroxisomal protein import.
    • 組織特異性Ubiquitous. Highest expression in pancreas, skeletal muscle and heart.
    • 関連疾患Defects in PEX7 are the cause of peroxisome biogenesis disorder complementation group 11 (PBD-CG11) [MIM:614879]. PBD refers to a group of peroxisomal disorders arising from a failure of protein import into the peroxisomal membrane or matrix. The PBD group is comprised of four disorders: Zellweger syndrome (ZWS), neonatal adrenoleukodystrophy (NALD), infantile Refsum disease (IRD), and classical rhizomelic chondrodysplasia punctata (RCDP). ZWS, NALD and IRD are distinct from RCDP and constitute a clinical continuum of overlapping phenotypes known as the Zellweger spectrum. The PBD group is genetically heterogeneous with at least 13 distinct genetic groups as concluded from complementation studies.
      Defects in PEX7 are the cause of rhizomelic chondrodysplasia punctata type 1 (RCDP1) [MIM:215100]. RCDP1 is characterized by rhizomelic shortening of femur and humerus, vertebral disorders, cataract, cutaneous lesions and severe mental retardation.
      Defects in PEX7 are the cause of peroxisome biogenesis disorder 9B (PBD9B) [MIM:614879]. A peroxisome biogenesis disorder with unusually mild clinical and biochemical manifestations. Affected individuals manifest a variable phenotype similar to, and in some cases indistinguishable from, classic Refsum disease. Variable features include ocular abnormalities, sensorimotor neuropathy, ichthyosis, deafness, chondrodysplasia punctata without rhizomelia or growth failure.
    • 配列類似性Belongs to the WD repeat peroxin-7 family.
      Contains 6 WD repeats.
    • 細胞内局在Peroxisome. Cytoplasm.
    • Information by UniProt
    • 参照データベース
    • 別名
      • PBD9B antibody
      • PCDP1 antibody
      • Peroxin 7 antibody
      • Peroxin-7 antibody
      • Peroxisomal PTS2 receptor antibody
      • Peroxisomal targeting signal 2 receptor antibody
      • Peroxisome biogenesis factor 7 antibody
      • Peroxisome targeting signal 2 receptor antibody
      • PEX7 antibody
      • PEX7 protein antibody
      • PEX7_HUMAN antibody
      • PTS2 receptor antibody
      • PTS2R antibody
      • RCDP1 antibody
      • RD antibody
      see all

    Anti-PEX7 antibody 画像

    • ab92779, at 1/50 dilution, staining PEX7 in paraffin-embedded Human breast carcinoma tissue by Immunohistochemistry in the presence (right panel) or absence (left panel) of immunising peptide.
    • All lanes : Anti-PEX7 antibody (ab92779) at 1/500 dilution

      Lane 1 : Extracts from NIH/3T3 cells
      Lane 2 : Extracts from NIH/3T3 cells with immunising peptide at 10 µg

      Lysates/proteins at 30 µg per lane.


      Predicted band size : 36 kDa

    Anti-PEX7 antibody (ab92779) 使用論文

    ab92779 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab92779.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"