製品の概要

  • 製品名Anti-PEX7 antibody
    PEX7 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to PEX7
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Chicken, Guinea pig, Cow, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 2-51 (SAVCGGAARM LRTPGRHGYA AEFSPYLPGR LACATAQHYG IAGCGTLLIL) of Human PEX7 (NP_000279).

  • ポジティブ・コントロール
    • MCF7 cell lysate

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab90822 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 36 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Binds to the N-terminal PTS2-type peroxisomal targeting signal and plays an essential role in peroxisomal protein import.
  • 組織特異性Ubiquitous. Highest expression in pancreas, skeletal muscle and heart.
  • 関連疾患Defects in PEX7 are the cause of peroxisome biogenesis disorder complementation group 11 (PBD-CG11) [MIM:614879]. PBD refers to a group of peroxisomal disorders arising from a failure of protein import into the peroxisomal membrane or matrix. The PBD group is comprised of four disorders: Zellweger syndrome (ZWS), neonatal adrenoleukodystrophy (NALD), infantile Refsum disease (IRD), and classical rhizomelic chondrodysplasia punctata (RCDP). ZWS, NALD and IRD are distinct from RCDP and constitute a clinical continuum of overlapping phenotypes known as the Zellweger spectrum. The PBD group is genetically heterogeneous with at least 13 distinct genetic groups as concluded from complementation studies.
    Defects in PEX7 are the cause of rhizomelic chondrodysplasia punctata type 1 (RCDP1) [MIM:215100]. RCDP1 is characterized by rhizomelic shortening of femur and humerus, vertebral disorders, cataract, cutaneous lesions and severe mental retardation.
    Defects in PEX7 are the cause of peroxisome biogenesis disorder 9B (PBD9B) [MIM:614879]. A peroxisome biogenesis disorder with unusually mild clinical and biochemical manifestations. Affected individuals manifest a variable phenotype similar to, and in some cases indistinguishable from, classic Refsum disease. Variable features include ocular abnormalities, sensorimotor neuropathy, ichthyosis, deafness, chondrodysplasia punctata without rhizomelia or growth failure.
  • 配列類似性Belongs to the WD repeat peroxin-7 family.
    Contains 6 WD repeats.
  • 細胞内局在Peroxisome. Cytoplasm.
  • Information by UniProt
  • 参照データベース
  • 別名
    • PBD9B antibody
    • PCDP1 antibody
    • Peroxin 7 antibody
    • Peroxin-7 antibody
    • Peroxisomal PTS2 receptor antibody
    • Peroxisomal targeting signal 2 receptor antibody
    • Peroxisome biogenesis factor 7 antibody
    • Peroxisome targeting signal 2 receptor antibody
    • PEX7 antibody
    • PEX7 protein antibody
    • PEX7_HUMAN antibody
    • PTS2 receptor antibody
    • PTS2R antibody
    • RCDP1 antibody
    • RD antibody
    see all

Anti-PEX7 antibody 画像

  • Anti-PEX7 antibody (ab90822) at 1 µg/ml (in 5% skim milk / PBS buffer) + MCF7 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 36 kDa

Anti-PEX7 antibody (ab90822) 使用論文

ab90822 has not yet been referenced specifically in any publications.

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