製品の概要

  • 製品名Anti-PEX14 antibody
    PEX14 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to PEX14
  • アプリケーション適用あり: IPmore details
    適用なし: WB
  • 種交差性
    交差種: Human
    交差が予測される動物種: Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • 免疫原

    Synthetic peptide corresponding to a region within amino acids 250-300 of Human PEX14 (NP_004556.1).

  • ポジティブ・コントロール
    • HeLa whole cell lysate

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab113286 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IP Use at 2-5 µg/mg of lysate.
  • 追加情報Is unsuitable for WB.
  • ターゲット情報

    • 機能Component of the peroxisomal translocation machinery with PEX13 and PEX17. Interacts with both the PTS1 and PTS2 receptors. Binds directly to PEX17.
    • 関連疾患Defects in PEX14 are the cause of peroxisome biogenesis disorder complementation group K (PBD-CGK) [MIM:601791]. PBD-CGK is a peroxisomal disorder arising from a failure of protein import into the peroxisomal membrane or matrix. The peroxisome biogenesis disorders (PBD group) are genetically heterogeneous with at least 14 distinct genetic groups as concluded from complementation studies. Include disorders are: Zellweger syndrome (ZWS), neonatal adrenoleukodystrophy (NALD), infantile Refsum disease (IRD), and classical rhizomelic chondrodysplasia punctata (RCDP). ZWS, NALD and IRD are distinct from RCDP and constitute a clinical continuum of overlapping phenotypes known as the Zellweger spectrum (PBD-ZSS).
      Defects in PEX14 are a cause of Zellweger syndrome (ZWS) [MIM:214100]. ZWS is a fatal peroxisome biogenesis disorder characterized by dysmorphic facial features, hepatomegaly, ocular abnormalities, renal cysts, hearing impairment, profound psychomotor retardation, severe hypotonia and neonatal seizures. Death occurs within the first year of life.
    • 配列類似性Belongs to the peroxin-14 family.
    • 細胞内局在Peroxisome membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • dJ734G22.2 antibody
      • NAPP2 antibody
      • NF E2 associated polypeptide 2 antibody
      • Peroxin 14 antibody
      • Peroxin-14 antibody
      • Peroxisomal biogenesis factor 14 antibody
      • Peroxisomal membrane anchor protein PEX14 antibody
      • Peroxisomal membrane anchor protein Pex14p antibody
      • Peroxisomal membrane protein PEX14 antibody
      • pex14 antibody
      • PEX14_HUMAN antibody
      • Pex14p antibody
      • PTS1 receptor docking protein antibody
      • PTS1 receptor-docking protein antibody
      see all

    Anti-PEX14 antibody 画像

    • Staining of PEX14 in HeLa whole cell lysate immunoprecipitated using ab113286 at 6 µg/mg lysate (1 mg/IP; 20% of IP loaded/lane). Lane 2: controle IgG. Predicted band size : 41 kDa. Exposure time: 10 seconds.

    Anti-PEX14 antibody (ab113286) 使用論文

    ab113286 has not yet been referenced specifically in any publications.

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