製品の概要

  • 製品名Anti-PEX14 antibody
    PEX14 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to PEX14
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse
    交差が予測される動物種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 120-150 of Human PEX14 (NP_004556.1).

  • ポジティブ・コントロール
    • Mouse Neuro 2a cell line lysates.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab112942 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 41 kDa.

ターゲット情報

  • 機能Component of the peroxisomal translocation machinery with PEX13 and PEX17. Interacts with both the PTS1 and PTS2 receptors. Binds directly to PEX17.
  • 関連疾患Defects in PEX14 are the cause of peroxisome biogenesis disorder complementation group K (PBD-CGK) [MIM:601791]. PBD-CGK is a peroxisomal disorder arising from a failure of protein import into the peroxisomal membrane or matrix. The peroxisome biogenesis disorders (PBD group) are genetically heterogeneous with at least 14 distinct genetic groups as concluded from complementation studies. Include disorders are: Zellweger syndrome (ZWS), neonatal adrenoleukodystrophy (NALD), infantile Refsum disease (IRD), and classical rhizomelic chondrodysplasia punctata (RCDP). ZWS, NALD and IRD are distinct from RCDP and constitute a clinical continuum of overlapping phenotypes known as the Zellweger spectrum (PBD-ZSS).
    Defects in PEX14 are a cause of Zellweger syndrome (ZWS) [MIM:214100]. ZWS is a fatal peroxisome biogenesis disorder characterized by dysmorphic facial features, hepatomegaly, ocular abnormalities, renal cysts, hearing impairment, profound psychomotor retardation, severe hypotonia and neonatal seizures. Death occurs within the first year of life.
  • 配列類似性Belongs to the peroxin-14 family.
  • 細胞内局在Peroxisome membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • dJ734G22.2 antibody
    • NAPP2 antibody
    • NF E2 associated polypeptide 2 antibody
    • Peroxin 14 antibody
    • Peroxin-14 antibody
    • Peroxisomal biogenesis factor 14 antibody
    • Peroxisomal membrane anchor protein PEX14 antibody
    • Peroxisomal membrane anchor protein Pex14p antibody
    • Peroxisomal membrane protein PEX14 antibody
    • pex14 antibody
    • PEX14_HUMAN antibody
    • Pex14p antibody
    • PTS1 receptor docking protein antibody
    • PTS1 receptor-docking protein antibody
    see all

Anti-PEX14 antibody 画像

  • Anti-PEX14 antibody (ab112942) at 1/100 dilution + Mouse Neuro 2a cell line lysates at 35 µg

    Predicted band size : 41 kDa

Anti-PEX14 antibody (ab112942) 使用論文

ab112942 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"