製品の概要

  • 製品名Anti-Pet1 antibody
    Pet1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Pet1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Horse, Chicken, Guinea pig, Cow, Drosophila melanogaster
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 35-84 (PLSPAVQKGSGQIQLWQFLLELLADRANAGCIAWEGGHGEFKLTDPDEV A) of Human Pet1 (NP_059991).

  • ポジティブ・コントロール
    • HeLa cell line lysate

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab108265 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 25 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Functions as a transcriptional regulator. According to PubMed:12761502, it functions as a transcriptional repressor. Functions in the differentiation and the maintenance of the central serotonergic neurons. May play a role in cell growth.
  • 組織特異性In brain, exclusively expressed in the major serotonergic neurons of the dorsal and median raphe nuclei located in the midbrain and pons. Also detected in prostate and small intestine.
  • 関連疾患Genetic variation in FEV may be associated with susceptibility to sudden infant death syndrome (SIDS) [MIM:272120]. SIDS remains elusive in its causes and devastating in its consequences. Despite the impressive decline in the incidence of SIDS since the recommendation to avoid the prone sleep position, SIDS remains a leading cause of death in the first year of life.
    Note=A chromosomal aberration involving FEV is found in Ewing tumors. Translocation t(2;21;22)(q23;q22;q12) that forms a EWSR1-FEV fusion protein with a potential oncogenic activity.
  • 配列類似性Belongs to the ETS family.
    Contains 1 ETS DNA-binding domain.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ETS-domain transcription factor antibody
    • FEV (ETS oncogene family) antibody
    • FEV antibody
    • FEV_HUMAN antibody
    • Fifth Ewing sarcoma variant antibody
    • Fifth Ewing variant protein antibody
    • HSRNAFEV antibody
    • mPet1 antibody
    • PC12 ETS domain-containing transcription factor 1 antibody
    • PC12 ETS factor 1 antibody
    • Pet-1 antibody
    • Protein FEV antibody
    see all

Anti-Pet1 antibody 画像

  • Anti-Pet1 antibody (ab108265) at 1 µg/ml + HeLa cell line lysate at 10 µg

    Predicted band size : 25 kDa

Anti-Pet1 antibody (ab108265) 使用論文

ab108265 has not yet been referenced specifically in any publications.

Product Wall

Thank you very much for your interest in ab108265 Anti-PET 1 antibody. To our knowledge this product has not been tested in rat. However a BLAST of the immunogen used showed 100% identity with rat. NP_653354.2Score = 106 bits (265), Expect = 3e-27,...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"