Recombinant full length protein (Rat) Peroxiredoxin 6
Rat and mouse lung, rat gut and kidney; human brain.
Staining pattern: cytoplasm of epithelial cells in the rat and
mouse lung, rat gut glandular cells and specific kidney
tubule cells. Achieves excellent staining of human brain
astrocytes in Parkinson's disease.
Involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. May play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.
Belongs to the ahpC/TSA family. Rehydrin subfamily. Contains 1 thioredoxin domain.
Cytoplasm. Lysosome. Cytoplasmic vesicle. Also found in lung secretory organelles.