製品の概要

  • 製品名Anti-Peroxiredoxin 6 antibody
    Peroxiredoxin 6 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Peroxiredoxin 6
  • 特異性This antibody is specific to the sulfinic and sulfonic form of PrxVI.
  • アプリケーション適用あり: WB, ICC/IFmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Sulfonylated peptide (KLH coupled) corresponding to the active site sequence common to mammalian Peroxiredoxin 6.

  • ポジティブ・コントロール
    • HeLa cell lysate.

アプリケーション

Our Abpromise guarantee covers the use of ab28444 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/2000. Predicted molecular weight: 25 kDa.
ICC/IF Use at an assay dependent dilution. PubMed: 18826942

ターゲット情報

  • 機能Involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. May play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.
  • 配列類似性Belongs to the ahpC/TSA family. Rehydrin subfamily.
    Contains 1 thioredoxin domain.
  • 細胞内局在Cytoplasm. Lysosome. Cytoplasmic vesicle. Also found in lung secretory organelles.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 1 Cys antibody
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    • Non-selenium glutathione peroxidase antibody
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    • p29 antibody
    • Peroxiredoxin-6 antibody
    • Peroxiredoxin6 antibody
    • PHGPx antibody
    • Phospholipase A2 lysosomal antibody
    • PLA2 antibody
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    • Prdx5 antibody
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    • PRDX6_HUMAN antibody
    • PRX antibody
    • Red blood cells page spot 12 antibody
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    see all

Anti-Peroxiredoxin 6 antibody 画像

  • All lanes : Anti-Peroxiredoxin 6 antibody (ab28444) at 1/2000 dilution

    Lane 1 : H2O2 untreated HeLa cell lysates
    Lane 2 : H2O2 treated HeLa cell lysates
    Lane 3 : Reduced recombinant Peroxiredoxin 6
    Lane 4 : Oxidised recombinant Peroxiredoxin 6


    Predicted band size : 25 kDa
    Observed band size : 28 kDa (why is the actual band size different from the predicted?)
  • All lanes : Anti Peroxiredoxin 6 antibody

    Lane 1 : H2O2 untreated HeLa cell lysate
    Lane 2 : H2O2 treated HeLa cell lysate
    Lane 3 : Reduced recombinant Peroxiredoxin 6
    Lane 4 : Oxidised recombinant Peroxiredoxin 6


    Predicted band size : 25 kDa
    Observed band size : 28 kDa (why is the actual band size different from the predicted?)

Anti-Peroxiredoxin 6 antibody (ab28444) 使用論文

This product has been referenced in:
  • O'Flaherty C & de Souza AR Hydrogen peroxide modifies human sperm peroxiredoxins in a dose-dependent manner. Biol Reprod 84:238-47 (2011). WB ; Human . Read more (PubMed: 20864641) »
  • Kim SY  et al. H2O2-dependent hyperoxidation of peroxiredoxin 6 (Prdx6) plays a role in cellular toxicity via up-regulation of iPLA2 activity. J Biol Chem 283:33563-8 (2008). ICC/IF ; Human . Read more (PubMed: 18826942) »

See all 2 Publications for this product

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