製品の概要

  • 製品名
    Anti-Peroxiredoxin 2 antibody
    Peroxiredoxin 2 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to Peroxiredoxin 2
  • 特異性
    This antibody is expected to recognize isoforms a and b only (NP_005800.3 and NP_859427.1 respectively).
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Human
    交差が予測される動物種: Rat, Cow, Cynomolgus monkey, Chinese hamster
  • 免疫原

    Synthetic peptide:

    C-NVDDSKEYFSKHN

    , corresponding to C terminal amino acids 186-198 of Human Peroxiredoxin 2

  • ポジティブ・コントロール
    • Human Brain and Mouse Brain lysates.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab50423 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 21 kDa (predicted molecular weight: 22 kDa).

ターゲット情報

  • 機能
    Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system. It is not able to receive electrons from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2).
  • 配列類似性
    Belongs to the ahpC/TSA family.
    Contains 1 thioredoxin domain.
  • 細胞内局在
    Cytoplasm.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Epididymis secretory sperm binding protein Li 2a antibody
    • HEL S 2a antibody
    • MGC4104 antibody
    • Natural killer cell enhancing factor B antibody
    • Natural killer cell-enhancing factor B antibody
    • Natural Killer Enhancing Factor B antibody
    • NKEF B antibody
    • NKEF-B antibody
    • NKEFB antibody
    • Peroxiredoxin-2 antibody
    • PRDX 2 antibody
    • PRDX2 antibody
    • PRDX2_HUMAN antibody
    • PrP antibody
    • PRX2 antibody
    • PRXII antibody
    • PTX1 antibody
    • TDPX1 antibody
    • Thiol Specific Antioxidant 1 antibody
    • Thiol specific antioxidant protein antibody
    • Thiol-specific antioxidant protein antibody
    • Thioredoxin Dependent Peroxide Reductase 1 antibody
    • Thioredoxin peroxidase 1 antibody
    • Thioredoxin-dependent peroxide reductase 1 antibody
    • Torin antibody
    • TPX1 antibody
    • TSA antibody
    see all

画像

プロトコール

参考文献

This product has been referenced in:
  • Wang HQ  et al. Differential phosphoprotein levels and pathway analysis identify the transition mechanism of LNCaP cells into androgen-independent cells. Prostate 70:508-17 (2010). Read more (PubMed: 19937597) »

See 1 Publication for this product

レビューと Q&A

Abcam has not validated the combination of species/application used in this Abreview.
Application
Western blot
Sample
Saccharomyces cerevisiae Cell lysate - whole cell (Whole cells from yeast)
Loading amount
8e+007 cells
Specification
Whole cells from yeast
Gel Running Conditions
Reduced Denaturing (10%)
Blocking step
Milk as blocking agent for 30 minute(s) · Concentration: 2% · Temperature: 20°C
Username

Miss. Heba Diab

Verified customer

投稿 Feb 02 2011

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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