製品の概要

  • 製品名Anti-Peroxiredoxin 1 antibody
    Peroxiredoxin 1 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to Peroxiredoxin 1
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Cow, Cynomolgus Monkey, Chinese Hamster
  • 免疫原

    Synthetic peptide:

    C-SDPKRTIAQDYG

    , corresponding to internal sequence amino acids 106-117 of Human Peroxiredoxin 1 (NP_859048.1)

  • ポジティブ・コントロール
    • IHC-P: placenta or thyroid tissue. WB: HepG2, HEK293 or A431 cell lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab109766 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.01 - 0.03 µg/ml. Detects a band of approximately 23-24 kDa (predicted molecular weight: 22 kDa).
IHC-P Use a concentration of 2.5 µg/ml.

ターゲット情報

  • 機能Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation.
  • 配列類似性Belongs to the ahpC/TSA family.
    Contains 1 thioredoxin domain.
  • 翻訳後修飾Phosphorylated on Thr-90 during the M-phase, which leads to a more than 80% decrease in enzymatic activity.
  • 細胞内局在Cytoplasm. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Heme binding 23 kDa protein antibody
    • MSP23 antibody
    • Natural killer cell-enhancing factor A antibody
    • NKEF A antibody
    • NKEF-A antibody
    • NKEFA antibody
    • OSF3 antibody
    • Osteoblast specific factor 3 antibody
    • PAG antibody
    • Paga antibody
    • PAGB antibody
    • Peroxiredoxin-1 antibody
    • PRDX1 antibody
    • PRDX1_HUMAN antibody
    • Proliferation associated gene A antibody
    • Proliferation-associated gene protein antibody
    • PRX1 antibody
    • PrxI antibody
    • TDPX2 antibody
    • Thioredoxin peroxidase 2 antibody
    • Thioredoxin-dependent peroxide reductase 2 antibody
    see all

Anti-Peroxiredoxin 1 antibody 画像

  • Anti-Peroxiredoxin 1 antibody (ab109766) at 0.01 µg/ml (incubation time: 1 hour) + HepG2 lysate in RIPA buffer at 35 µg
    Developed using the ECL technique

    Predicted band size : 22 kDa
  • ab109766 at 2.5µg/ml staining Peroxiredoxin 1 in formalin-fixed, paraffin-embedded Human placenta tissue.
  • ab109766 at 2.5µg/ml staining Peroxiredoxin 1 in formalin-fixed, paraffin-embedded Human thyroid tissue.

Anti-Peroxiredoxin 1 antibody (ab109766) 使用論文

ab109766 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"