Anti-Periostin 抗体 (ab92460)
Key features and details
- Rabbit polyclonal to Periostin
- Suitable for: WB, ICC/IF, IHC-P
- Reacts with: Mouse, Rat, Chicken, Human
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
-
製品名
Anti-Periostin antibody
Periostin 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Periostin -
由来種
Rabbit -
アプリケーション
適用あり: WB, ICC/IF, IHC-Pmore details -
種交差性
交差種: Mouse, Rat, Chicken, Human
交差が予測される動物種: Bird, Fish, Mammals, Amphibian -
免疫原
Synthetic peptide corresponding to Mouse Periostin. Synthetic peptide from the fasciclin domain 1 of mouse periostin.
Database link: Q62009 -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
Constituent: PBS -
Concentration information loading...
-
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab92460の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
WB | (1) |
1/1000. Predicted molecular weight: 93 kDa.
|
ICC/IF |
Use at an assay dependent concentration.
|
|
IHC-P |
Use at an assay dependent concentration.
|
特記事項 |
---|
WB
1/1000. Predicted molecular weight: 93 kDa. |
ICC/IF
Use at an assay dependent concentration. |
IHC-P
Use at an assay dependent concentration. |
ターゲット情報
-
機能
Binds to heparin. Induces cell attachment and spreading and plays a role in cell adhesion. May play a role in extracellular matrix mineralization. -
組織特異性
Widely expressed with highest levels in aorta, stomach, lower gastrointestinal tract, placenta, uterus and breast. Up-regulated in epithelial ovarian tumors. Not expressed in normal ovaries. Also highly expressed at the tumor periphery of lung carcinoma tissue but not within the tumor. Overexpressed in breast cancers. -
配列類似性
Contains 1 EMI domain.
Contains 4 FAS1 domains. -
翻訳後修飾
Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium. -
細胞内局在
Secreted > extracellular space > extracellular matrix. - Information by UniProt
-
参照データベース
- Entrez Gene: 10631 Human
- Entrez Gene: 50706 Mouse
- Entrez Gene: 361945 Rat
- Omim: 608777 Human
- SwissProt: Q15063 Human
- SwissProt: Q62009 Mouse
- Unigene: 136348 Human
- Unigene: 721018 Human
see all -
別名
- Fasciclin-I like antibody
- MGC119510 antibody
- MGC119511 antibody
see all
画像
データシートおよび資料
-
Datasheet download
参考文献 (18)
ab92460 は 18 報の論文で使用されています。
- Li J et al. Non-invasive measurement of tumor immune microenvironment and prediction of survival and chemotherapeutic benefits from 18F fluorodeoxyglucose PET/CT images in gastric cancer. Front Immunol 13:1019386 (2022). PubMed: 36311742
- Kerschan-Schindl K et al. Differential Expression of Dickkopf 1 and Periostin in Mouse Strains with High and Low Bone Mass. Biology (Basel) 11:N/A (2022). PubMed: 36552348
- Ganieva U et al. Involvement of Transcription Factor 21 in the Pathogenesis of Fibrosis in Endometriosis. Am J Pathol 190:145-157 (2020). PubMed: 31610174
- Jiang Y et al. Tumor Immune Microenvironment and Chemosensitivity Signature for Predicting Response to Chemotherapy in Gastric Cancer. Cancer Immunol Res 7:2065-2073 (2019). PubMed: 31615816
- Gonzalez L et al. Hyperglycemia Aggravates Diet-Induced Coronary Artery Disease and Myocardial Infarction in SR-B1-Knockout/ApoE-Hypomorphic Mice. Front Physiol 9:1398 (2018). PubMed: 30356742