製品の概要

  • 製品名
  • 製品の詳細
    Goat polyclonal to PEBP4
  • アプリケーション
    適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide:

    C-RERASEPKHKNQAE

    , corresponding to C terminal amino acids 210-223 of Human PEBP4 (NP_659399.2).

  • ポジティブ・コントロール
    • Human Heart lysates.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファー
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • 特記事項(精製)
    ab99468 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG

アプリケーション

Our Abpromise guarantee covers the use of ab99468 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 26 kDa. An additional band of unknown identity was also consistently observed at 30kDa. This band was successfully blocked by incubation with the immunizing peptide.
IHC-P Use at an assay dependent concentration. PubMed: 21887552

ターゲット情報

  • 関連性
    PEBP4 appears to promote cellular resistance to TNF-induced apoptosis by inhibiting activation of the Raf-1/MEK/ERK pathway, JNK and phosphatidylethanolamine externalization.
  • 細胞内局在
    Lysosome
  • 参照データベース
  • 別名
    • 1700051A02Rik antibody
    • 1700081D17Rik antibody
    • AI429082 antibody
    • CORK 1 antibody
    • CORK1 antibody
    • Cousin of RKIP 1 protein antibody
    • GWTM1933 antibody
    • hPEBP4 antibody
    • MGC22776 antibody
    • PEBP 4 antibody
    • Phosphatidylethanolamine binding protein 4 antibody
    • PRO4408 antibody
    • Protein cousin of RKIP 1 antibody
    • UNQ1933/PRO4408 antibody
    see all

画像

  • ab99468 (5μg/ml) staining of PEBP4 in paraffin embedded Human Pancreas following microwaved antigen retrieval with Tris/EDTA

    buffer pH9 and  HRP-staining and shows staining consistant with lysosomes.

  • Anti-PEBP4 antibody (ab99468) at 1 µg/ml + Human Heart lysates at 35 µg

    Predicted band size : 26 kDa

参考文献

This product has been referenced in:
  • Li H  et al. Phosphatidylethanolamine-binding protein 4 is associated with breast cancer metastasis through Src-mediated Akt tyrosine phosphorylation. Oncogene N/A:N/A (2013). IHC-P ; Human . Read more (PubMed: 24276246) »
  • Yu GP  et al. The expression of PEBP4 protein in lung squamous cell carcinoma. Tumour Biol 32:1257-63 (2011). WB, IHC-P ; Human . Read more (PubMed: 21887552) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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