Anti-AS3 抗体 (ab84918)
Key features and details
- Rabbit polyclonal to AS3
- Suitable for: IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
製品の概要
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製品名
Anti-AS3 antibody
AS3 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to AS3 -
由来種
Rabbit -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差種: Mouse, Human
交差が予測される動物種: Chimpanzee, Gorilla, Orangutan -
免疫原
Synthetic peptide corresponding to Human AS3 aa 1200-1300.
Database link: Q9NTI5 -
ポジティブ・コントロール
- Human controls: Breast Carcinoma, Ovarian Carcinoma, Prostate Carcinoma, Skin Basal Cell Carcinoma, Testicular Seminoma Mouse control: Squamous Cell Carcinoma
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 6.8
Preservative: 0.09% Sodium azide
Constituents: 0.1% BSA, Tris buffered saline -
Concentration information loading...
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精製度
Immunogen affinity purified -
特記事項(精製)
ab84918 was affinity purified using an epitope specific to AS3 immobilized on solid support. Antibody concentration was determined by extinction coefficient: absorbance at 280 nm of 1.4 equals 1.0 mg of IgG. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab84918の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-P |
特記事項 |
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Likely to work with frozen sections.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
ターゲット情報
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機能
Regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Plays a role in androgen-induced proliferative arrest in prostate cells. -
組織特異性
Widely expressed. -
配列類似性
Belongs to the PDS5 family.
Contains 3 A.T hook DNA-binding domains.
Contains 1 HEAT repeat. -
細胞内局在
Nucleus. - Information by UniProt
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参照データベース
- Entrez Gene: 23047 Human
- Entrez Gene: 100710 Mouse
- Omim: 605333 Human
- SwissProt: Q9NTI5 Human
- SwissProt: Q4VA53 Mouse
- Unigene: 744901 Human
- Unigene: 32959 Mouse
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別名
- AI646570 antibody
- Androgen induced proliferation inhibitor antibody
- Androgen-induced proliferation inhibitor antibody
see all
画像
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ab84918, at a 1/100 dilution, staining AS3 in formalin fixed, paraffin embedded human prostate carcinoma by Immunohistochemistry. Detection: a Red fluorescent goat anti-rabbit IgG highly cross adsorbed antibody at a dilution of 1/100.
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ab84918, at a 1/250 dilution, staining AS3 in formalin fixed, paraffin embedded human prostate carcinoma by Immunohistochemistry, using DAB staining.
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ab84918, at a 1/250 dilution, staining AS3 in formalin fixed, paraffin embedded mouse squamous cell carcinoma by Immunohistochemistry, using DAB staining.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab84918 は 1 報の論文で使用されています。
- Brieño-Enríquez MA et al. Cohesin Removal along the Chromosome Arms during the First Meiotic Division Depends on a NEK1-PP1?-WAPL Axis in the Mouse. Cell Rep 17:977-986 (2016). PubMed: 27760328