製品の概要

  • 製品名Anti-PDLIM7 antibody
    PDLIM7 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to PDLIM7
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-458 of Human PDLIM7

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab56504 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能May function as a scaffold on which the coordinated assembly of proteins can occur. May play a role as an adapter that, via its PDZ domain, localizes LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Involved in both of the two fundamental mechanisms of bone formation, direct bone formation (e.g. embryonic flat bones mandible and cranium), and endochondral bone formation (e.g. embryonic long bone development). Plays a role during fracture repair. Involved in BMP6 signaling pathway.
    • 組織特異性Isoform 1 and isoform 2 are expressed ubiquitously, however, isoform 2 predominates in skeletal muscle, isoform 1 is more abundant in lung, spleen, leukocytes and fetal liver.
    • 配列類似性Contains 3 LIM zinc-binding domains.
      Contains 1 PDZ (DHR) domain.
    • ドメインThe LIM zinc-binding 2 (LIM 2) domain interacts with TBX4.
      The LIM zinc-binding 3 (LIM 3) domain provides the structural basis for recognition of tyrosine-containing tight turn structures. This domain is necessary and sufficient for interaction with TBX5.
      Anchored to cell periphery via its N-terminal PDZ domain.
    • 細胞内局在Cytoplasm. Cytoplasm > cytoskeleton. Colocalizes with RET to the cell periphery and in some cytoskeletal components. Colocalizes with TPM2 near the Z line in muscle. Co-localizes with TBX4 and TBX5 to actin filaments.
    • Information by UniProt
    • 参照データベース
    • 別名
      • 1110003B01Rik antibody
      • Enigma antibody
      • LIM domain protein antibody
      • LIM domain protein enigma antibody
      • LIM mineralization protein 1 antibody
      • Lim mineralization protein 3 antibody
      • LIM mineralization protein antibody
      • LMP 1 antibody
      • LMP antibody
      • LMP1 antibody
      • LMP3 antibody
      • PDLI7_HUMAN antibody
      • PDLIM 7 antibody
      • Pdlim7 antibody
      • PDZ and LIM doamin protein 7 antibody
      • PDZ and LIM domain 7 antibody
      • PDZ and LIM domain protein 7 antibody
      • Protein enigma antibody
      see all

    Anti-PDLIM7 antibody 画像



    • Predicted band size : 21 kDa
      PDLIM7 antibody (ab56504) at 1ug/lane + HeLa cell lysate at 25ug/lane.

    Anti-PDLIM7 antibody (ab56504) 使用論文

    This product has been referenced in:
    • Yi CR  et al. Systematic analysis of bacterial effector-postsynaptic density 95/disc large/zonula occludens-1 (PDZ) domain interactions demonstrates Shigella OspE protein promotes protein kinase C activation via PDLIM proteins. J Biol Chem 289:30101-13 (2014). Read more (PubMed: 25124035) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"