製品の概要

  • 製品名
    Anti-PDLIM5 antibody
    PDLIM5 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to PDLIM5
  • 由来種
    Rabbit
  • アプリケーション
    適用あり: WB, IPmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Dog, Pig, Xenopus laevis, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Xenopus tropicalis
  • 免疫原

    Synthetic peptide dessigned within residues: EAGDM FLEA LGYTWH DTC FVCSVCC ES LEGQTFFS K KDKPLCKKH AHSVNF, corresponding to C terminal amino acids 546-596 of Human PDLIM5 (NP_006448.2)

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
  • ポジティブ･コントロール
    • HeLa whole cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab85967 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/2000 - 1/10000. Predicted molecular weight: 64 kDa.
IP Use at 2-5 µg/mg of lysate.

ターゲット情報

  • 機能
    May play an important role in the heart development by scaffolding PKC to the Z-disk region. May play a role in the regulation of cardiomyocyte expansion. Overexpression promotes the development of heart hypertrophy. Contributes to the regulation of dendritic spine morphogenesis in neurons. May restrain postsynaptic growth of excitatory synapses.
  • 組織特異性
    Heart and skeletal muscle specific. Expression is commonly increased in the brain of patients with bipolar disorder, schizophrenia, and major depression.
  • 配列類似性
    Contains 3 LIM zinc-binding domains.
    Contains 1 PDZ (DHR) domain.
  • 細胞内局在
    Cell junction > synapse > postsynaptic cell membrane > postsynaptic density. Cell junction > synapse > synaptosome. Cytoplasm. Detected both at presynaptic and postsynaptic sites.
  • Information by UniProt
  • 参照データベース
    see all
  • 別名
    • ENH antibody
    • ENH1 antibody
    • Enigma homolog antibody
    • Enigma like LIM domain protein antibody
    • Enigma like PDZ and LIM domains protein antibody
    • Enigma-like PDZ and LIM domains protein antibody
    • L 9 antibody
    • L9 antibody
    • LIM antibody
    • PDLI5_HUMAN antibody
    • PDLIM5 antibody
    • PDZ and LIM domain 5 antibody
    • PDZ and LIM domain protein 5 antibody
    see all

画像

  • Western blot - PDLIM5 antibody (ab85967)
    Western blot - PDLIM5 antibody (ab85967)
    All lanes : Anti-PDLIM5 antibody (ab85967) at 0.04 µg/ml

    Lane 1 : HeLa whole cell lysate at 50 µg
    Lane 2 : HeLa whole cell lysate at 15 µg
    Lane 3 : HeLa whole cell lysate at 5 µg

    Predicted band size: 64 kDa


    Exposure time: 30 seconds
  • Immunoprecipitation - PDLIM5 antibody (ab85967)
    Immunoprecipitation - PDLIM5 antibody (ab85967)
    1mg HeLa whole cell lysate was immunoprecipitated using ab85967 at 3µg. 20% of IP was loaded/lane and PDLIM5 was detected with ab85967 at 1µg/ml (lane 1) or a control IgG (lane 2).
    Detection: chemiluminescence with exposure time of 10 seconds.

参考文献

ab85967 has not yet been referenced specifically in any publications.

ab85967 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

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