Anti-PDGFR alpha 抗体 [APA5] (ab90967)
Key features and details
- Rat monoclonal [APA5] to PDGFR alpha
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Isotype: IgG2a
Related conjugates and formulations
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
-
製品名
Anti-PDGFR alpha antibody [APA5]
PDGFR alpha 一次抗体 製品一覧 -
製品の詳細
Rat monoclonal [APA5] to PDGFR alpha -
由来種
Rat -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Mouse -
免疫原
Fusion protein corresponding to Mouse PDGFR alpha (extracellular). Fusion protein containing the extracellular domain of Mouse PDGFR alpha and the Fc portion of Human IgG1 purified from the culture supernatant of transfected COS1 cells
-
ポジティブ・コントロール
- Flow Cyt: Mouse NIH3T3 cells.
-
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.20
Preservative: 0.09% Sodium azide
Constituents: PBS, 0.87% Sodium chloride -
Concentration information loading...
-
精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
APA5 -
アイソタイプ
IgG2a -
軽鎖の種類
kappa -
研究分野
関連製品
-
Alternative Versions
-
Compatible Secondaries
-
Conjugation kits
-
Isotype control
-
Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab90967の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
Flow Cyt |
Use 1µg for 106 cells.
ab18450 - Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
特記事項 |
---|
Flow Cyt
Use 1µg for 106 cells. ab18450 - Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
ターゲット情報
-
機能
Receptor that binds both PDGFA and PDGFB and has a tyrosine-protein kinase activity. -
組織特異性
Expressed in primary and metastatic colon tumors and in normal colon tissue. Tumors may express a different isoform to that found in normal tissue. -
関連疾患
Note=A chromosomal aberration involving PDGFRA is found in some cases of hypereosinophilic syndrome. Interstitial chromosomal deletion del(4)(q12q12) causes the fusion of FIP1L1 and PDGFRA (FIP1L1-PDGFRA). -
配列類似性
Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
Contains 5 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 protein kinase domain. -
細胞内局在
Membrane. - Information by UniProt
-
参照データベース
- Entrez Gene: 18595 Mouse
- SwissProt: P26618 Mouse
- Unigene: 221403 Mouse
-
別名
- Alpha-type platelet-derived growth factor receptor antibody
- CD140 antigen-like family member A antibody
- CD140a antibody
see all
画像
プロトコール
データシートおよび資料
-
Datasheet download
参考文献 (12)
ab90967 は 12 報の論文で使用されています。
- Gould E & Kim JH SCN2A contributes to oligodendroglia excitability and development in the mammalian brain. Cell Rep 36:109653 (2021). PubMed: 34496232
- Wang L et al. Telocytes inhibited inflammatory factor expression and enhanced cell migration in LPS-induced skin wound healing models in vitro and in vivo. J Transl Med 18:60 (2020). PubMed: 32028987
- Jiang L et al. Direct Tumor Killing and Immunotherapy through Anti-SerpinB9 Therapy. Cell 183:1219-1233.e18 (2020). PubMed: 33242418
- Foster DS et al. Elucidating the fundamental fibrotic processes driving abdominal adhesion formation. Nat Commun 11:4061 (2020). PubMed: 32792541
- Jang M et al. Oligodendrocytes regulate presynaptic properties and neurotransmission through BDNF signaling in the mouse brainstem. Elife 8:N/A (2019). PubMed: 30998186