Anti-PDGFR alpha 抗体 [16A1] (ab96569)
Key features and details
- Mouse monoclonal [16A1] to PDGFR alpha
- Suitable for: ICC, Flow Cyt, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG1
Related conjugates and formulations
製品の概要
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製品名
Anti-PDGFR alpha antibody [16A1]
PDGFR alpha 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [16A1] to PDGFR alpha -
由来種
Mouse -
アプリケーション
適用あり: ICC, Flow Cyt, IHC-Pmore details -
種交差性
交差種: Mouse, Human -
免疫原
Tissue, cells or virus corresponding to Human PDGFR alpha. CD140a-transfected NIH 3T3 cells
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特記事項
This product was changed from ascites to tissue culture supernatant. Please note that the dilutions may need to be adjusted accordingly. If you have any questions, please do not hesitate to contact our scientific support team.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 7.40
Preservative: 0.097% Sodium azide
Constituent: PBS -
Concentration information loading...
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精製度
Protein A purified -
特記事項(精製)
Purified from TCS -
ポリ/モノ
モノクローナル -
クローン名
16A1 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Alternative Versions
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Compatible Secondaries
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Conjugation kits
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab96569の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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ICC |
Use at an assay dependent concentration.
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Flow Cyt |
Use at an assay dependent concentration.
ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
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IHC-P |
Use at an assay dependent concentration.
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特記事項 |
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ICC
Use at an assay dependent concentration. |
Flow Cyt
Use at an assay dependent concentration. ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
IHC-P
Use at an assay dependent concentration. |
ターゲット情報
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機能
Receptor that binds both PDGFA and PDGFB and has a tyrosine-protein kinase activity. -
組織特異性
Expressed in primary and metastatic colon tumors and in normal colon tissue. Tumors may express a different isoform to that found in normal tissue. -
関連疾患
Note=A chromosomal aberration involving PDGFRA is found in some cases of hypereosinophilic syndrome. Interstitial chromosomal deletion del(4)(q12q12) causes the fusion of FIP1L1 and PDGFRA (FIP1L1-PDGFRA). -
配列類似性
Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
Contains 5 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 protein kinase domain. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 5156 Human
- Entrez Gene: 18595 Mouse
- Omim: 173490 Human
- SwissProt: P16234 Human
- SwissProt: P26618 Mouse
- Unigene: 74615 Human
- Unigene: 221403 Mouse
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別名
- Alpha-type platelet-derived growth factor receptor antibody
- CD140 antigen-like family member A antibody
- CD140a antibody
see all
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (7)
ab96569 は 7 報の論文で使用されています。
- Wang W et al. 4,8-dicarboxyl-8,9-iridoid-1-glycoside Promotes Neural Stem Cell Differentiation Through MeCP2. Dose Response 20:15593258221112959 (2022). PubMed: 35958275
- Cui F et al. Spindle pole body component 25 and platelet-derived growth factor mediate crosstalk between tumor-associated macrophages and prostate cancer cells. Front Immunol 13:907636 (2022). PubMed: 35967419
- Chao FL et al. Fluoxetine Promotes Hippocampal Oligodendrocyte Maturation and Delays Learning and Memory Decline in APP/PS1 Mice. Front Aging Neurosci 12:627362 (2020). PubMed: 33519426
- Gazit VA et al. Stem cell and niche regulation in human short bowel syndrome. JCI Insight 5:N/A (2020). PubMed: 33141758
- Huber AK et al. Immobilization after injury alters extracellular matrix and stem cell fate. J Clin Invest 130:5444-5460 (2020). PubMed: 32673290
- Cai W et al. Limited Regeneration Potential with Minimal Epicardial Progenitor Conversions in the Neonatal Mouse Heart after Injury. Cell Rep 28:190-201.e3 (2019). PubMed: 31269439
- Debnath S et al. Discovery of a periosteal stem cell mediating intramembranous bone formation. Nature 562:133-139 (2018). PubMed: 30250253