製品の概要

製品の詳細

  • 由来Synthetic

特性

Our Abpromise guarantee covers the use of ab65452 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking

  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

関連情報

  • 別名
    • 5''-cyclic phosphodiesterase 8A
    • cAMP specific cyclic nucleotide phosphodiesterase 8A
    • FLJ16150
    • High affinity cAMP specific and IBMX insensitive 3'5' cyclic phosphodiesterase 8A
    • High affinity cAMP-specific and IBMX-insensitive 3''
    • HsT19550
    • PDE 8A
    • PDE8A
    • PDE8A_HUMAN
    • Phosphodiesterase 8A
    • Phosphodiesterase8A
    • Weakly similar to 3'5' cyclic nucleotide phosphodiesterase
    see all
  • 機能Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development.
  • 組織特異性Expressed in most tissues except thymus and peripheral blood leukocytes. Highest levels in testis, ovary, small intestine and colon.
  • パスウェイPurine metabolism; 3',5'-cyclic AMP degradation; AMP from 3',5'-cyclic AMP: step 1/1.
  • 配列類似性Belongs to the cyclic nucleotide phosphodiesterase family. PDE8 subfamily.
    Contains 1 PAC (PAS-associated C-terminal) domain.
    Contains 1 PAS (PER-ARNT-SIM) domain.
  • ドメインComposed of a C-terminal catalytic domain containing two putative divalent metal sites and an N-terminal regulatory domain.
  • Information by UniProt

PDE8A peptide (ab65452) 使用論文

ab65452 has not yet been referenced specifically in any publications.

Product Wall

ab65448 corresponde a una secuencia de aminoácidos alrededor de la zona N terminal de la proteína. Sin embargo, ab65452 pertenece a una secuencia en torno a la zona C terminal de la proteína.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"