The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
5''-cyclic phosphodiesterase 8A
cAMP specific cyclic nucleotide phosphodiesterase 8A
High affinity cAMP specific and IBMX insensitive 3'5' cyclic phosphodiesterase 8A
High affinity cAMP-specific and IBMX-insensitive 3''
Weakly similar to 3'5' cyclic nucleotide phosphodiesterase
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development.
Expressed in most tissues except thymus and peripheral blood leukocytes. Highest levels in testis, ovary, small intestine and colon.