製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to PDE8A
  • アプリケーション
    適用あり: WB, IPmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    Synthetic cyclic peptide, corresponding to the mid region of PDE8A.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab14619 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
IP
  • 追加情報
    IP: 1/250.
    WB: 1/500. Detects a band of approximately 98-102 kDa.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development.
    • 組織特異性
      Expressed in most tissues except thymus and peripheral blood leukocytes. Highest levels in testis, ovary, small intestine and colon.
    • パスウェイ
      Purine metabolism; 3',5'-cyclic AMP degradation; AMP from 3',5'-cyclic AMP: step 1/1.
    • 配列類似性
      Belongs to the cyclic nucleotide phosphodiesterase family. PDE8 subfamily.
      Contains 1 PAC (PAS-associated C-terminal) domain.
      Contains 1 PAS (PER-ARNT-SIM) domain.
    • ドメイン
      Composed of a C-terminal catalytic domain containing two putative divalent metal sites and an N-terminal regulatory domain.
    • Information by UniProt
    • 参照データベース
    • 別名
      • 5''-cyclic phosphodiesterase 8A antibody
      • cAMP specific cyclic nucleotide phosphodiesterase 8A antibody
      • FLJ16150 antibody
      • High affinity cAMP specific and IBMX insensitive 3'5' cyclic phosphodiesterase 8A antibody
      • High affinity cAMP-specific and IBMX-insensitive 3'' antibody
      • HsT19550 antibody
      • PDE 8A antibody
      • PDE8A antibody
      • PDE8A_HUMAN antibody
      • Phosphodiesterase 8A antibody
      • Phosphodiesterase8A antibody
      • Weakly similar to 3'5' cyclic nucleotide phosphodiesterase antibody
      see all

    参考文献

    This product has been referenced in:
    • Kelly MP  et al. Select 3',5'-cyclic nucleotide phosphodiesterases exhibit altered expression in the aged rodent brain. Cell Signal 26:383-397 (2013). Mouse, Rat . Read more (PubMed: 24184653) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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