製品の概要

  • 製品名Anti-PDE8A antibody
    PDE8A 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to PDE8A
  • アプリケーション適用あり: WB, IPmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide corresponding to a region between residue 779 and 829 of Human PDE8A (NP_002596.1).

  • ポジティブ・コントロール
    • HeLa and 293T whole cell lysates.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.09% Sodium Azide
    Constituents: Tris citrate/phosphate, pH 7-8
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab109597 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/2000 - 1/10000. Predicted molecular weight: 93 kDa.
IP Use at 2-5 µg/mg of lysate.

ターゲット情報

  • 機能Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development.
  • 組織特異性Expressed in most tissues except thymus and peripheral blood leukocytes. Highest levels in testis, ovary, small intestine and colon.
  • パスウェイPurine metabolism; 3',5'-cyclic AMP degradation; AMP from 3',5'-cyclic AMP: step 1/1.
  • 配列類似性Belongs to the cyclic nucleotide phosphodiesterase family. PDE8 subfamily.
    Contains 1 PAC (PAS-associated C-terminal) domain.
    Contains 1 PAS (PER-ARNT-SIM) domain.
  • ドメインComposed of a C-terminal catalytic domain containing two putative divalent metal sites and an N-terminal regulatory domain.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 5''-cyclic phosphodiesterase 8A antibody
    • cAMP specific cyclic nucleotide phosphodiesterase 8A antibody
    • FLJ16150 antibody
    • High affinity cAMP specific and IBMX insensitive 3'5' cyclic phosphodiesterase 8A antibody
    • High affinity cAMP-specific and IBMX-insensitive 3'' antibody
    • HsT19550 antibody
    • PDE 8A antibody
    • PDE8A antibody
    • PDE8A_HUMAN antibody
    • Phosphodiesterase 8A antibody
    • Phosphodiesterase8A antibody
    • Weakly similar to 3'5' cyclic nucleotide phosphodiesterase antibody
    see all

Anti-PDE8A antibody 画像

  • All lanes : Anti-PDE8A antibody (ab109597) at 0.1 µg/ml

    Lane 1 : HeLa cell lysate at 50 µg
    Lane 2 : HeLa cell lysate at 15 µg
    Lane 3 : HeLa cell lysate at 5 µg
    Lane 4 : 293T cell lysate at 50 µg


    Predicted band size : 93 kDa
  • Detection of PDE8A by Western Blot of Immunprecipitate.
    Lane 1: ab109597 at 1µg/ml staining PDE8A in HeLa whole cell lysate immunoprecipitated using ab109597 at 6µg/mg lysate (1 mg/IP; 20% of IP loaded/lane).
    Lane 2: Control IgG
    Detection: Chemiluminescence with exposure time of 30 seconds.

Anti-PDE8A antibody (ab109597) 使用論文

ab109597 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab109597.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"