製品の概要

  • 製品名Anti-PDE6 beta antibody
    PDE6 beta 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to PDE6 beta
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Horse, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within C terminal amino acids 372-421 (RQHEHVIHLM DIAIIATDLA LYFKKRAMFQ KIVDESKNYQ DKKSWVEYLS) of Human PDE6 beta (NP_001138764).

  • ポジティブ・コントロール
    • 293T cell lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab125381 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 66 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能This protein participates in processes of transmission and amplification of the visual signal. Necessary for the formation of a functional phosphodiesterase holoenzyme.
  • 関連疾患Defects in PDE6B are the cause of retinitis pigmentosa type 40 (RP40) [MIM:613801]. RP40 is a retinal dystrophy belonging to the group of pigmentary retinopathies. Retinitis pigmentosa is characterized by retinal pigment deposits visible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of cone photoreceptors. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.
    Defects in PDE6B are a cause of congenital stationary night blindness autosomal dominant type 2 (CSNBAD2) [MIM:163500]; also known as congenital stationary night blindness Rambusch type. Congenital stationary night blindness is a non-progressive retinal disorder characterized by impaired night vision.
  • 配列類似性Belongs to the cyclic nucleotide phosphodiesterase family.
    Contains 2 GAF domains.
  • 細胞内局在Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 5''-cyclic phosphodiesterase subunit beta antibody
    • Congenital stationary night blindness 3 autosomal dominant antibody
    • CSNB 3 antibody
    • CSNB3 antibody
    • CSNBAD2 antibody
    • GMP PDE beta antibody
    • GMP-PDE beta antibody
    • PDE 6 beta antibody
    • PDE 6B antibody
    • PDE6B antibody
    • PDE6B_HUMAN antibody
    • PDEB antibody
    • Phosphodiesterase 6B antibody
    • Phosphodiesterase 6B cGMP specific rod beta antibody
    • Rd 1 antibody
    • Rd1 antibody
    • Rod cGMP phosphodiesterase beta subunit antibody
    • Rod cGMP specific 3' 5' cyclic phosphodiesterase beta subunit antibody
    • Rod cGMP-specific 3'' antibody
    • RP40 antibody
    see all

Anti-PDE6 beta antibody 画像

  • Anti-PDE6 beta antibody (ab125381) at 1 µg/ml + 293T cell lysate at 10 µg

    Secondary
    Goat anti-Rabbit IgG HRP

    Predicted band size : 66 kDa

Anti-PDE6 beta antibody (ab125381) 使用論文

ab125381 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting Abcam regarding ab125381.

The lab is currently re-testing this antibody in WB to verify the correct molecular weight band. I will let you know once we have this data. Thank you for your patience.

Please do...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"