Anti-PDE6 alpha 抗体 (ab61820)

製品の概要

• 製品名
  Anti-PDE6 alpha antibody
  PDE6 alpha 一次抗体 製品一覧
• 製品の詳細
  Rabbit polyclonal to PDE6 alpha
• アプリケーション
  適用あり: IHC-Pmore details
• 種交差性
  交差種: Human
  
• 免疫原

  Synthetic peptide corresponding to Human PDE6 alpha (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH).

• ポジティブ･コントロール
  • Human retina tissue
• 特記事項
  For short term storage: at -4°C

製品の特性

• 製品の状態
  Liquid
• 保存方法
  Shipped at 4°C. Upon delivery aliquot. Avoid freeze / thaw cycle.
• バッファー
  Preservative: 0.1% Sodium Azide
  Constituents: PBS, pH 7.7
• Concentration information loading...
• 精製度
  Immunogen affinity purified
• ポリ/モノ
  ポリクローナル
• アイソタイプ
  IgG
• 研究分野
  • Signal Transduction
  • Second Messenger
  • Nucleotide Messenger
  • cAMP

  • Signal Transduction
  • Second Messenger
  • Nucleotide Messenger
  • cGMP

  • Neuroscience
  • Sensory System
  • Visual system

関連製品

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

アプリケーション

ターゲット情報

• 機能
  This protein participates in processes of transmission and amplification of the visual signal.
• 関連疾患
  Defects in PDE6A are the cause of retinitis pigmentosa type 43 (RP43) [MIM:613810]. RP43 is a retinal dystrophy belonging to the group of pigmentary retinopathies. Retinitis pigmentosa is characterized by retinal pigment deposits visible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of cone photoreceptors. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.
• 配列類似性
  Belongs to the cyclic nucleotide phosphodiesterase family.
  Contains 2 GAF domains.
• 細胞内局在
  Cell membrane.

• Target information above from: UniProt accession P16499 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 参照データベース
  • Entrez Gene: 5145 Human
  • Omim: 180071 Human
  • SwissProt: P16499 Human
  • Unigene: 151710 Human
  • Unigene: 567314 Human
• 別名
  • 5''-cyclic phosphodiesterase subunit alpha antibody
  • CGPR A antibody
  • GMP PDE alpha antibody

  • GMP-PDE alpha antibody
  • PDE 6 alpha antibody
  • PDE 6A antibody
  • PDE V B1 antibody
  • PDE V-B1 antibody
  • PDE6A antibody
  • PDE6A_HUMAN antibody
  • PDEA antibody
  • Phosphodiesterase 6 alpha antibody
  • Phosphodiesterase 6A alpha subunit antibody
  • Phosphodiesterase 6A antibody
  • Phosphodiesterase 6A cGMP specific rod alpha antibody
  • Retinal Rod Photoreceptor cGMP Phosphodiesterase alpha antibody
  • Rod cGMP specific 3' 5' cyclic phosphodiesterase alpha subunit antibody
  • Rod cGMP-specific 3'' antibody

  see all

プロトコール

• Immunohistochemistry protocols