製品の概要

  • 製品名Anti-PDE6 alpha antibody
    PDE6 alpha 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to PDE6 alpha
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Sheep, Cow
    交差が予測される動物種: Mouse, Chicken, Human
  • 免疫原

    Synthetic peptide corresponding to Human PDE6C aa 16-29.
    Sequence:

    MPQFAKEYFDRKLR


    (Peptide available as ab5863)

  • ポジティブ・コントロール
    • WB: sheep retinal extract.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab5660 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500. Detects a band of approximately 90 kDa.Can be blocked with PDE6C peptide (ab5863).

ターゲット情報

  • 機能This protein participates in processes of transmission and amplification of the visual signal.
  • 関連疾患Defects in PDE6A are the cause of retinitis pigmentosa type 43 (RP43) [MIM:613810]. RP43 is a retinal dystrophy belonging to the group of pigmentary retinopathies. Retinitis pigmentosa is characterized by retinal pigment deposits visible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of cone photoreceptors. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.
  • 配列類似性Belongs to the cyclic nucleotide phosphodiesterase family.
    Contains 2 GAF domains.
  • 細胞内局在Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 5''-cyclic phosphodiesterase subunit alpha antibody
    • CGPR A antibody
    • GMP PDE alpha antibody
    • GMP-PDE alpha antibody
    • PDE 6 alpha antibody
    • PDE 6A antibody
    • PDE V B1 antibody
    • PDE V-B1 antibody
    • PDE6A antibody
    • PDE6A_HUMAN antibody
    • PDEA antibody
    • Phosphodiesterase 6 alpha antibody
    • Phosphodiesterase 6A alpha subunit antibody
    • Phosphodiesterase 6A cGMP specific rod alpha antibody
    • Retinal Rod Photoreceptor cGMP Phosphodiesterase alpha antibody
    • Rod cGMP specific 3' 5' cyclic phosphodiesterase alpha subunit antibody
    • Rod cGMP-specific 3'' antibody
    see all

Anti-PDE6 alpha antibody 画像

  • Western blot of PDE6C on sheep retinal extracts using ab5660.

Anti-PDE6 alpha antibody (ab5660) 使用論文

ab5660 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"