製品の概要

  • 製品名Anti-PDE4DIP antibody
    PDE4DIP 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to PDE4DIP
  • アプリケーション適用あり: WB, IHC-P, ICC/IFmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 26-171 of Human PDE4DIP, isoform 2 (Q5VU43-2).

  • ポジティブ・コントロール
    • Human duodenum tissue; RT4 and U251 MG lysates.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab121375 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/250 - 1/500.
IHC-P 1/10 - 1/20. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF Use a concentration of 1 - 4 µg/ml.

Fixation/Permeabilization: PFA/Triton X-100.

ターゲット情報

  • 機能May function as an anchor sequestering components of the cAMP-dependent pathway to Golgi and/or centrosomes.
  • 組織特異性Highly expressed in heart and skeletal muscle and to a lower extent in brain and placenta.
  • 関連疾患Note=A chromosomal aberration involving PDE4DIP may be the cause of a myeloproliferative disorder (MBD) associated with eosinophilia. Translocation t(1;5)(q23;q33) that forms a PDE4DIP-PDGFRB fusion protein.
  • 配列類似性Contains 1 NBPF domain.
  • 発生段階Expressed in fetal heart.
  • 細胞内局在Golgi apparatus. Cytoplasm > cytoskeleton > centrosome. Cytoplasm. Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Cardiomyopathy associated protein 2 antibody
    • Cardiomyopathy-associated protein 2 antibody
    • CMYA2 antibody
    • MMGL antibody
    • MYOME_HUMAN antibody
    • Myomegalin antibody
    • Pde4dip antibody
    • Phosphodiesterase 4D interacting protein antibody
    • Phosphodiesterase 4D-interacting protein antibody
    see all

Anti-PDE4DIP antibody 画像

  • Immunocytochemistry/Immunofluorescence analysis of A-431 cells labelling PDE4DIP with ab121375 shows positivity in the Golgi apparatus.

  • ab121375 at 1/15 dilution staining PDE4DIP in Paraffin-embedded Human Duodenum tissue by Immunohistochemistry.
  • All lanes : Anti-PDE4DIP antibody (ab121375) at 1/250 dilution

    Lane 1 : RT4 lysate
    Lane 2 : U251 MG lysate
    Lane 3 : Human plasma
    Lane 4 : Human liver lysate
    Lane 5 : Human tonsil lysate

    Developed using the ECL technique

Anti-PDE4DIP antibody (ab121375) 使用論文

ab121375 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting Abcam.

Because we carry over 70,000 products, it isn't feasible for us to keep small sample sizes of our products.

We are happy to reassure our customers that all of our products are covered by our Abpromise, ...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"