製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to PDE4C
  • 特異性
    This antibody detects 3 isoforms of PDE4C subclasses (PDE4C1, PDE4C2 and PDE4C3).
  • アプリケーション
    適用あり: IP, WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic cyclic peptide (carboxy-terminal peptide common to all PDE4C proteins).

  • ポジティブ・コントロール
    • recombinant protein PDE4C1/2

法規制情報

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファー
    Preservative: 0.02% Thimerosal / Merthiolate
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab14608 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IP 1/20.
WB 1/500. Predicted molecular weight: 80 kDa.Can be blocked with PDE4C peptide (ab169990).

ターゲット情報

  • 機能
    Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.
  • 組織特異性
    Expressed in various tissues but not in cells of the immune system.
  • パスウェイ
    Purine metabolism; 3',5'-cyclic AMP degradation; AMP from 3',5'-cyclic AMP: step 1/1.
  • 配列類似性
    Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 5''-cyclic phosphodiesterase 4C antibody
    • cAMP specific 3' 5' cyclic phosphodiesterase 4C antibody
    • cAMP-specific 3'' antibody
    • DPDE 1 antibody
    • DPDE1 antibody
    • MGC126222 antibody
    • PDE 21 antibody
    • PDE 4C antibody
    • PDE21 antibody
    • Pde4c antibody
    • PDE4C_HUMAN antibody
    • Phosphodiesterase 4C antibody
    • Phosphodiesterase 4C cAMP specific antibody
    • Phosphodiesterase 4C, cAMP specific (phosphodiesterase E1 dunce homolog, Drosophila) antibody
    • Phosphodiesterase E1 dunce homolog antibody
    • Phosphodiesterase E1 dunce homolog Drosophila antibody
    • Phosphodiesterase type 4C antibody
    see all

Anti-PDE4C antibody (ab14608) 使用論文

ab14608 has not yet been referenced specifically in any publications.

Product Wall

Application
Western blot
Sample
Rat Cell lysate - whole cell (Astrocytes)
Loading amount
40 µg
Specification
Astrocytes
Gel Running Conditions
Reduced Denaturing (12)
Blocking step
BSA as blocking agent for 2 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
Username

Abcam user community

Verified customer

投稿 Jan 24 2013

Thank you for your enquiry. 1) PDE4A antibody (ab14607) does not cross react to any known PDE4 subtype except all the PDE4A subtype variants including PDE4A1, A5, Ax, A8, it has little or no reactivity towards PDE4A10 and PDE4A11. We have tested fo...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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