製品の概要

  • 製品名Anti-PDE1C antibody
    PDE1C 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to PDE1C
  • 特異性The antibody does not cross react with PDE1A, PDE1B or other PDEs.
  • アプリケーション適用あり: WB, IP, IHC-Pmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide (N terminal).

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab14602 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/250 - 1/500. Predicted molecular weight: 70 kDa. This antibody labels multiple bands in the 70-87 kDa range all believed to be various PDE1C variants.
IP Use at an assay dependent concentration.
IHC-P Use at an assay dependent concentration. PubMed: 19924104

ターゲット情報

  • 機能Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a high affinity for both cAMP and cGMP.
  • 組織特異性Expressed in several tissues, including brain and heart.
  • 配列類似性Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 5''-cyclic nucleotide phosphodiesterase 1C antibody
    • Calcium/calmodulin dependent 3'5' cyclic nucleotide phosphodiesterase 1C antibody
    • Calcium/calmodulin-dependent 3'' antibody
    • Cam PDE 1C antibody
    • Cam-PDE 1C antibody
    • hCam 3 antibody
    • hCam-3 antibody
    • HCAM3 antibody
    • HSPDE1C1A antibody
    • Human 3'5' cyclic nucleotide Phosphodiesterase antibody
    • PDE 1C antibody
    • Pde1c antibody
    • PDE1C_HUMAN antibody
    • Phosphodiesterase 1C antibody
    • Phosphodiesterase 1C calmodulin dependent antibody
    • Phosphodiesterase 1C calmodulin dependent 70kDa antibody
    see all

Anti-PDE1C antibody 画像

  • All lanes : Anti-PDE1C antibody (ab14602) at 1/500 dilution

    Lane 1 : Brain lysate
    Lane 2 : Heart lysate
    Lane 3 : Lung lysate
    Lane 4 : Testis lysate
    Lane 5 : Kidney lysate


    Predicted band size : 70 kDa

Anti-PDE1C antibody (ab14602) 使用論文

This product has been referenced in:
  • Giachini FR  et al. Decreased cGMP level contributes to increased contraction in arteries from hypertensive rats: role of phosphodiesterase 1. Hypertension 57:655-63 (2011). WB ; Rat . Read more (PubMed: 21282562) »
  • Lee AC  et al. Olfactory marker protein is critical for functional maturation of olfactory sensory neurons and development of mother preference. J Neurosci 31:2974-82 (2011). WB ; Mouse . Read more (PubMed: 21414919) »

See all 3 Publications for this product

Product Wall

Thank you for your enquiry. I am sorry to hear you are having a problem with ab14602. I would like to suggest the following modifications to your protocol: Perhaps playing with the milk concentration in the primary antibody solution may help. Re...

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Thank you for your enquiry. I have added a very useful paper to the datasheet for this antibody which will describe the different PEDC1 splice variants in mouse, and their tissue specificity. Yan C et al. The calmodulin-dependent phosphodiesteras...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"