製品の概要

  • 製品名Anti-PDE1A antibody
    PDE1A 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to PDE1A
  • アプリケーション適用あり: IP, WB, IHC-Pmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    Synthetic peptides (conserved sequence near the N-terminal) unique to PDE1A family members.

  • ポジティブ・コントロール
    • Rat testis.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab14599 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IP 1/200.
WB 1/250 - 1/500. Predicted molecular weight: 61 kDa. This antibody labels multiple bands in 65-72 kDa range all believed to be various PDE1A variants expressed in various rat tissues.
IHC-P Use at an assay dependent concentration. PubMed: 19924104

ターゲット情報

  • 機能Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a higher affinity for cGMP than for cAMP.
  • 組織特異性Several tissues, including brain, kidney, testes and heart.
  • 配列類似性Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 3' 5' cyclic nucleotide phosphodiesterase antibody
    • 5''-cyclic nucleotide phosphodiesterase 1A antibody
    • 61 kDa Cam PDE antibody
    • 61 kDa Cam-PDE antibody
    • Calcium/calmodulin dependent 3' 5' cyclic nucleotide phosphodiesterase 1A antibody
    • Calcium/Calmodulin stimulated cyclic nucleotide phosphodiesterase antibody
    • Calcium/calmodulin-dependent 3'' antibody
    • Calmodulin-dependent Phosphodiesterase antibody
    • Cam PDE 1A antibody
    • Cam-PDE 1A antibody
    • CAM-PDE-1A antibody
    • HCAM 1 antibody
    • hCam-1 antibody
    • HCAM1 antibody
    • HSPDE1A antibody
    • MGC26303 antibody
    • PDE 1A antibody
    • PDE1A antibody
    • PDE1A_HUMAN antibody
    • Phosphodiesterase 1A antibody
    • Phosphodiesterase 1A calmodulin dependent antibody
    see all

Anti-PDE1A antibody (ab14599) 使用論文

This product has been referenced in:
  • Giachini FR  et al. Decreased cGMP level contributes to increased contraction in arteries from hypertensive rats: role of phosphodiesterase 1. Hypertension 57:655-63 (2011). WB ; Rat . Read more (PubMed: 21282562) »
  • Wang X  et al. Cyclic nucleotide signaling in polycystic kidney disease. Kidney Int 77:129-40 (2010). IHC-P ; Mouse, Rat . Read more (PubMed: 19924104) »

See all 3 Publications for this product

Product Wall

Thank you for contacting Abcam.

The peptide for ab14599 has now added been added to the catalogue as PDE1A peptide (ab140070). Also the immnuogen for ab14599 was from human PDE1A N-terminal epitope form *******.
If there is anything else I...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"