製品の概要

  • 製品名Anti-PDE12 antibody
    PDE12 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to PDE12
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    KLH conjugated synthetic peptide corresponding to a region within C terminal amino acids 369-398 of Human PDE12 (NP_808881.3).

  • ポジティブ・コントロール
    • MDA-MB231 cell line lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab107000 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 67 kDa.

ターゲット情報

  • 機能Enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. This enzyme degraded triphosphorylated 2-5A to produce AMP and ATP. Also cleaves 3',5'-phosphodiester bond of oligoadenylates. Play a role as a negative regulator of the The 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons (IFNs). Suppression of this enzyme induces reduction of viral replication in Hela cells, thus counteracting the antiviral pathway probably by inhibiting the 2-5A system.
  • 組織特異性Ubiquitous.
  • 配列類似性Belongs to the CCR4/nocturin family.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 2 PDE antibody
    • 2' 5' phosphodiesterase 12 antibody
    • 2' phosphodiesterase antibody
    • 2',5'-phosphodiesterase 12 antibody
    • 2'-PDE antibody
    • 2-PDE antibody
    • 2PDE antibody
    • DKFZp667B1218 antibody
    • Pde12 antibody
    • PDE12_HUMAN antibody
    • Phosphodiesterase 12 antibody
    see all

Anti-PDE12 antibody 画像

  • Anti-PDE12 antibody (ab107000) at 1/100 dilution + MDA-MB231 cell line lysate at 35 µg

    Predicted band size : 67 kDa

Anti-PDE12 antibody (ab107000) 使用論文

ab107000 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab107000.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"