製品の概要

  • 製品名
  • 製品の詳細
    Goat polyclonal to PD1
  • アプリケーション
    適用あり: ELISA, WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Cow, Dog
  • 免疫原

    Synthetic peptide:

    GELDFQWREKTPE

    , corresponding to Internal sequence amino acids 224-236 of Human PDCD1

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab36151 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA Use at an assay dependent concentration.
WB Use a concentration of 2 - 6 µg/ml. Predicted molecular weight: 32 kDa.

ターゲット情報

  • 機能
    Possible cell death inducer, in association with other factors.
  • 関連疾患
    Genetic variation in PDCD1 is associated with susceptibility to systemic lupus erythematosus type 2 (SLEB2) [MIM:605218]. Systemic lupus erythematosus is a chronic, inflammatory and often febrile multisystemic disorder of connective tissue. It affects principally the skin, joints, kidneys and serosal membranes. It is thought to represent a failure of the regulatory mechanisms of the autoimmune system.
  • 配列類似性
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • 発生段階
    Induced at programmed cell death.
  • 細胞内局在
    Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CD279 antibody
    • CD279 antigen antibody
    • hPD 1 antibody
    • hPD l antibody
    • hPD-1 antibody
    • hSLE1 antibody
    • PD 1 antibody
    • PD-1 antibody
    • PD1 antibody
    • PDCD 1 antibody
    • PDCD1 antibody
    • PDCD1_HUMAN antibody
    • Programmed cell death 1 antibody
    • Programmed cell death 1 protein antibody
    • Programmed cell death protein 1 antibody
    • Protein PD 1 antibody
    • Protein PD-1 antibody
    • SLEB2 antibody
    • Systemic lupus erythematosus susceptibility 2 antibody
    see all

Anti-PD1 antibody 画像

プロトコール

Anti-PD1 antibody (ab36151) 使用論文

This product has been referenced in:
  • Baban B  et al. Upregulation of Programmed Death-1 and Its Ligand in Cardiac Injury Models: Interaction with GADD153. PLoS One 10:e0124059 (2015). IF, Flow Cyt . Read more (PubMed: 25902191) »

See 1 Publication for this product

Product Wall

Abreviews
Abcam has not validated the combination of species/application used in this Abreview.
Application
Western blot
Sample
Dog Recombinant protein (human PD-1)
Gel Running Conditions
Reduced Denaturing
Loading amount
0.25 µg
Specification
human PD-1
Blocking step
BSA as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 3% · Temperature: 4°C
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投稿 Sep 07 2017

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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