製品の概要

  • 製品名Anti-PCYT1A antibody [EPR3940(2)]
    PCYT1A 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [EPR3940(2)] to PCYT1A
  • アプリケーション適用あり: WB, IHC-P, ICCmore details
    適用なし: Flow Cyt or IP
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Synthetic peptide within Human PCYT1A aa 1-100. The exact sequence is proprietary.
    Database link: P49585

  • ポジティブ・コントロール
    • WB: HepG2, HeLa, A549, and K562 cell lysates IHC-P: Human colon and Human prostatic hyperplasia tissue
  • 特記事項

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab109263 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000 - 1/10000. Predicted molecular weight: 42 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
ICC 1/50 - 1/100.
  • 追加情報Is unsuitable for Flow Cyt or IP.
  • ターゲット情報

    • 機能Controls phosphatidylcholine synthesis.
    • パスウェイPhospholipid metabolism; phosphatidylcholine biosynthesis; phosphatidylcholine from phosphocholine: step 1/2.
    • 配列類似性Belongs to the cytidylyltransferase family.
    • 翻訳後修飾The serine residues of the C-terminus are phosphorylated. The inactive soluble form is stabilized by phosphorylation, the active membrane bound form is promoted by anionic lipids or diacylglycerol, and is stabilized by dephosphorylation.
    • 細胞内局在Cytoplasm > cytosol. Membrane. It can interconvert between an inactive cytosolic form and an active membrane-bound form.
    • Information by UniProt
    • 参照データベース
    • 別名
      • CCT A antibody
      • CCT alpha antibody
      • CCT-alpha antibody
      • Choline phosphate cytidylyltransferase A antibody
      • Choline-phosphate cytidylyltransferase A antibody
      • CT A antibody
      • CT antibody
      • CTP:phosphocholine cytidylyltransferase A antibody
      • CTPCT antibody
      • PCY1A_HUMAN antibody
      • PCYT1 antibody
      • Pcyt1a antibody
      • Phosphate cytidylyltransferase 1 choline alpha antibody
      • Phosphate cytidylyltransferase 1 choline alpha isoform antibody
      • Phosphorylcholine transferase A antibody
      see all

    Anti-PCYT1A antibody [EPR3940(2)] 画像

    • All lanes : Anti-PCYT1A antibody [EPR3940(2)] (ab109263) at 1/1000 dilution

      Lane 1 : HepG2 cell lysate
      Lane 2 : HeLa cell lysate
      Lane 3 : A549 cell lysate
      Lane 4 : K562 cell lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 42 kDa
      Observed band size : 42 kDa
    • ab109263, at a 1/50 dilution, staining PCYT1A in paraffin embedded Human colon tissue by Immunohistochemistry.
    • ab109263, at a 1/50 dilution, staining PCYT1A in paraffin embedded Human prostatic hyperplasia by Immunohistochemistry.

    Anti-PCYT1A antibody [EPR3940(2)] (ab109263) 使用論文

    This product has been referenced in:
    • Payne F  et al. Mutations disrupting the Kennedy phosphatidylcholine pathway in humans with congenital lipodystrophy and fatty liver disease. Proc Natl Acad Sci U S A 111:8901-6 (2014). WB ; Human . Read more (PubMed: 24889630) »

    See 1 Publication for this product

    Product Wall

    There are currently no Abreviews or Questions for ab109263.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"