製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to PCSK9
  • アプリケーション
    適用あり: ICC/IF, WBmore details
  • 種交差性
    交差種: Mouse, Rat, Human
    交差が予測される動物種: Chimpanzee, Macaque monkey, Gorilla, Common marmoset
  • 免疫原

    Synthetic peptide from Mouse PCSK9 amino acids 152-163

    VFAQSIPWNLER

  • ポジティブ・コントロール
    • HepG2 cells

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab95478 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF 1/50.
WB Use at an assay dependent dilution. Predicted molecular weight: 74 kDa.

ターゲット情報

  • 機能
    May be implicated in the differentiation of cortical neurons and may play a role in cholesterol homeostasis.
  • 組織特異性
    Expressed in neuro-epithelioma, colon carcinoma, hepatic and pancreatic cell lines, and in Schwann cells.
  • 関連疾患
    Defects in PCSK9 are the cause of familial hypercholesterolemia 3 (FH3) [MIM:603776]. FH3 inheritance is autosomal dominant.
  • 配列類似性
    Belongs to the peptidase S8 family.
    Contains 1 peptidase S8 domain.
  • 翻訳後修飾
    The soluble zymogen undergoes autocatalytic intramolecular processing in the endoplasmic reticulum, resulting in the cleavage of its propeptide that remains associated with the secreted enzyme.
  • 細胞内局在
    Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Convertase subtilisin/kexin type 9 preproprotein antibody
    • FH3 antibody
    • HCHOLA3 antibody
    • Hypercholesterolemia autosomal dominant 3 antibody
    • LDLCQ1 antibody
    • NARC 1 antibody
    • NARC-1 antibody
    • NARC1 antibody
    • Neural apoptosis regulated convertase 1 antibody
    • Neural apoptosis-regulated convertase 1 antibody
    • PC 9 antibody
    • PC9 antibody
    • PCSK 9 antibody
    • PCSK9 antibody
    • PCSK9_HUMAN antibody
    • Proprotein convertase 9 antibody
    • Proprotein convertase PC9 antibody
    • Proprotein convertase subtilisin/kexin type 9 antibody
    • PSEC0052 antibody
    • Subtilisin/kexin like protease PC9 antibody
    • Subtilisin/kexin-like protease PC9 antibody
    see all

Anti-PCSK9 antibody 画像

  • ab95478 staining PCSK9 in HepG2 cells by immunofluorescence. The positive staining cytoplasm was visualized in red with a Cy3 conjugated goat anti-rabbit secondary antibody.

Anti-PCSK9 antibody (ab95478) 使用論文

ab95478 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab95478.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録