製品の概要

製品の詳細

  • 由来
    Synthetic
  • アミノ酸配列
    • 生物種
      Human
    • 配列
      C-NAWKQNLNKVKN
    • 領域
      355 to 366

関連製品

特性

Our Abpromise guarantee covers the use of ab45824 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking - Blocking peptide for Anti-PCID1 antibody (ab40829)

  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

関連情報

  • 別名
    • B5
    • B5 receptor
    • Dendritic cell protein
    • eIF3m
    • EIF3M_HUMAN
    • Eukaryotic translation initiation factor 3 subunit M
    • Fetal lung protein B5
    • FLJ29030
    • GA17
    • hfl B5
    • hFL-B5
    • PCI domain containing 1 (herpesvirus entry mediator)
    • PCI domain-containing protein 1
    • PCID1
    • TANGO7
    see all
  • 機能
    Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. May favor virus entry in case of infection with herpes simplex virus 1 (HSV1) or herpes simplex virus 2 (HSV2).
  • 組織特異性
    Broadly expressed.
  • 配列類似性
    Belongs to the eIF-3 subunit M family.
    Contains 1 PCI domain.
  • 細胞内局在
    Cytoplasm.
  • Information by UniProt

参考文献

ab45824 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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